Chemistry of renieramycins. Part 3.(1) isolation and structure of stabilized renieramycin type derivatives possessing antitumor activity from Thai sponge Xestospongia species, pretreated with potassium cyanide.

Suwanborirux K; Amnuoypol S; Plubrukarn A; Pummangura S; Kubo A; Tanaka C; Saito N

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Chemistry of renieramycins. Part 3.(1) isolation and structure of stabilized renieramycin type derivatives possessing antitumor activity from Thai sponge Xestospongia species, pretreated with potassium cyanide.

机译：雷尼霉素的化学。第3.（1）部分，从氰化钾预处理的泰国海绵种橡胶海绵中分离出具有抗肿瘤活性的稳定的雷尼霉素类衍生物，并对其结构进行了研究。

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Renieramycins M (1m) and N (1n) were isolated from the Thai sponge Xestospongia sp., pretreated with potassium cyanide in methanolic buffer solution, and their structures and relative stereochemistries were elucidated on the basis of spectroscopic data. This strategy is the first example of the gram-scale preparation of this series of compounds and presents a potential solution for increasing the gram-scale supply of novel natural products from marine sources.

机译：从泰国海绵Xestospongia sp。中分离出了瑞尼霉素M（1m）和N（1n），并在甲醇缓冲溶液中用氰化钾预处理，并根据光谱数据阐明了它们的结构和相对立体化学。该策略是该系列化合物的克级制备的第一个例子，并且为增加海洋来源的新型天然产物的克级供应提供了一种潜在的解决方案。

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来源
《Journal of natural products》 |2003年第11期|共6页
作者
Suwanborirux K; Amnuoypol S; Plubrukarn A; Pummangura S; Kubo A; Tanaka C; Saito N;
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正文语种 eng
中图分类药学;
关键词
Potassium; Porifera; Cyanides; structure; Part; 钾; 多孔动物门; 氰化物;

机译：Potassium;Porifera;Cyanides;structure;Part;钾;多孔动物门;氰化物;

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1. Chemistry of renieramycins. Part 3.(1) isolation and structure of stabilized renieramycin type derivatives possessing antitumor activity from Thai sponge Xestospongia species, pretreated with potassium cyanide. [J] . Suwanborirux K, Amnuoypol S, Plubrukarn A, Journal of natural products . 2003,第11期

机译：雷尼霉素的化学。第3.（1）部分，从氰化钾预处理的泰国海绵种橡胶海绵中分离出具有抗肿瘤活性的稳定的雷尼霉素类衍生物，并对其结构进行了研究。
2. Chemistry of renieramycins. Part 13: Isolation and structure of stabilized renieramycin type derivatives, renieramycins W-Y, from Philippine blue sponge Xestospongia sp., pretreated with potassium cyanide [J] . Tatsukawa M., Punzalan L.L.C., Magpantay H.D.S., Tetrahedron . 2012,第36期

机译：雷尼霉素的化学。第13部分：菲律宾蓝海绵Xestospongia sp。稳定化的瑞尼霉素类衍生物瑞尼霉素W-Y的分离和结构，经氰化钾预处理
3. Chemistry of Renieramycins.Part 5.Structure Elucidation of Renieramycin-Type Derivatives O,Q,R,and S from Thai Marine Sponge Xestospongia Species Pretreated with Potassium Cyanide [J] . Surattana Amnuoypol, Khanit Suwanborirux, Sunibhond Pummangura Journal of natural products . 2004,第6期

机译：雷尼霉素的化学。第5部分。氰化钾预处理的泰国海洋海绵橡胶海绵中雷尼霉素型衍生物O，Q，R和S的结构阐明
4. Peloruside B a Potent Antitumor Macrolide from the New Zealand Marine Sponge Mycale hentscheli: Isolation Structure Total Synthesis and Bioactivity [O] . A. Jonathan Singh, Chun-Xiao Xu, Xiaoming Xu, -1

机译：来自新西兰海绵Mycale Hentscheli的强大抗肿瘤大啰嗦：隔离结构总合成和生物活性
5. Chemistry of Renieramycins. Part 3. Isolation and Structure of Stabilized Renieramycin Type Derivatives Possessing Antitumor Activity from Thai Sponge Xestospongia Species Pretreated with Potassium Cyanide [O] . -1

机译：Renieramycins的化学。第3部分。稳定的renieramycin型衍生物的分离和结构具有来自泰国海绵Xestospongia物种的抗肿瘤活性，用氰化钾预处理

Chemistry of renieramycins. Part 3.(1) isolation and structure of stabilized renieramycin type derivatives possessing antitumor activity from Thai sponge Xestospongia species, pretreated with potassium cyanide.

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