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Natural oil nanoemulsions as cores for layer-by-layer encapsulation

机译:天然油纳米乳液为核心,用于逐层封装

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摘要

In this study, emulsions of three different natural oils were prepared using spontaneous emulsification technique. The effect of three emulsifiers, AOT, lecithin and cholesterol on emulsion properties was studied. Their influence on interfacial tension at oil/water interface was evaluated by the pendant drop shape analysis method. Then, the mean droplet size, zeta potential and stability of emulsions were investigated in relation with the type of oil, surfactant, oil-to-ethanol ratio and surfactant concentration. We found that in the case of linseed oil, fine emulsion droplets are formed without any surfactant due to its low oil/water interfacial tension. A hydrophobic dye (Coumarin 6) was encapsulated within oil cores and its presence was confirmed by fluorescence spectroscopy and microscopy. The obtained emulsions can be used alone or as the cores for layer-by-layer encapsulation, which was demonstrated by enclosing droplets within first layer of synthetic polycation poly(allyamine hydrochloride) (PAH).
机译:在这项研究中,使用自发乳化技术制备了三种不同天然油的乳液。研究了三种乳化剂,AOT,卵磷脂和胆固醇对乳化性能的影响。通过悬垂液滴形状分析方法评估了它们对油/水界面界面张力的影响。然后,根据油的类型,表面活性剂,油与乙醇的比例和表面活性剂的浓度,研究了乳液的平均液滴尺寸,ζ电势和稳定性。我们发现,在亚麻籽油的情况下,由于其低的油/水界面张力而形成的细小乳液液滴没有任何表面活性剂。将疏水性染料(Coumarin 6)包裹在油核中,并通过荧光光谱和显微镜检查确认其存在。所获得的乳液可单独使用或用作逐层封装的核心,这通过将液滴封闭在合成聚阳离子聚(烯丙胺盐酸盐)(PAH)的第一层中来证明。

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