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Encapsulation of cosmetic active ingredients for topical application - a review

机译:用于局部应用的化妆品活性成分的封装-评论

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摘要

Microencapsulation is finding increasing applications in cosmetics and personal care markets. This article provides an overall discussion on encapsulation of cosmetically active ingredients and encapsulation techniques for cosmetic and personal care products for topical applications. Some of the challenges are identified and critical aspects and future perspectives are addressed. Many cosmetics and personal care products contain biologically active substances that require encapsulation for increased stability of the active materials. The topical and transdermal delivery of active cosmetic ingredients requires effective, controlled and safe means of reaching the target site within the skin. Preservation of the active ingredients is also essential during formulation, storage and application of the final cosmetic product. Microencapsulation offers an ideal and unique carrier system for cosmetic active ingredients, as it has the potential to respond to all these requirements. The encapsulated agent can be released by several mechanisms, such as mechanical action, heat, diffusion, pH, biodegradation and dissolution. The selection of the encapsulation technique and shell material depends on the final application of the product, considering physical and chemical stability, concentration, required particle size, release mechanism and manufacturing costs.
机译:微囊化在化妆品和个人护理市场中发现越来越多的应用。本文提供了有关化妆品活性成分的封装以及用于局部应用的化妆品和个人护理产品的封装技术的整体讨论。确定了一些挑战,并解决了关键方面和未来的观点。许多化妆品和个人护理产品包含生物活性物质,需要对其进行封装以提高活性物质的稳定性。活性化妆品成分的局部和透皮递送需要有效,受控和安全的方式到达皮肤内的目标部位。活性成分的保存在最终化妆品的配制,储存和使用过程中也至关重要。微囊化为化妆品活性成分提供了理想且独特的载体系统,因为它有可能满足所有这些要求。包封的试剂可以通过多种机制释放,例如机械作用,热,扩散,pH,生物降解和溶解。封装技术和外壳材料的选择取决于产品的最终应用,并考虑物理和化学稳定性,浓度,所需的粒径,释放机理和制造成本。

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