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首页> 外文期刊>Journal of Microencapsulation: Microcapsules Liposomes Nanoparticles Microcells Microspheres >Enhanced payload and photo-protection for pesticides using nanostructured lipid carriers with corn oil as liquid lipid
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Enhanced payload and photo-protection for pesticides using nanostructured lipid carriers with corn oil as liquid lipid

机译：使用以玉米油为液态脂质的纳米结构脂质载体，增强了农药的有效负载和光保护作用

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摘要

With the aim to establish a novel nanocarrier system with higher payload and higher photo-protection for deltamethrin (active ingredient) compared to solid lipid nanoparticles (SLN), nanostructured lipid carriers (NLC) were prepared by combining hot homogenization and sonication with different ratios of corn oil (liquid lipid) and beeswax (solid lipid). Compared to SLN, the incorporation of corn oil gave a higher payload, slower release rate and higher photo-protection for deltamethrin. Particularly, compared to beeswax solid lipid nanoparticles (BSLN), NLC gave a higher payload (approximately 1.79 times) with a high encapsulation efficiency (83.6%), higher photo-protection in direct photolysis (1.8 times) after 12 h exposure of ultraviolet light (UV) and in indirect photolysis (1.37 times) after 2 h exposure of UV in 2% (v/v) acetone solution used as a photosensitizer. This study demonstrated that novel nanocarrier possesses a wide range of applicability in protecting photo-labile compounds for the crop, food and pharmaceutical industries.
机译：为了建立一种新颖的纳米载体系统，与固体脂质纳米颗粒（SLN）相比，其对溴氰菊酯（活性成分）具有更高的有效负载和更高的光保护作用，通过将热均质化和超声处理以不同的比例混合来制备纳米结构的脂质载体（NLC）。玉米油（液体脂质）和蜂蜡（固体脂质）。与SLN相比，玉米油的掺入提供了更高的有效负载，更慢的释放速率和更高的溴氰菊酯光保护作用。特别是，与蜂蜡固体脂质纳米颗粒（BSLN）相比，NLC的有效载荷更高（约1.79倍），封装效率更高（83.6％），在紫外线照射12 h后直接光解中的光保护更高（1.8倍）。 （UV）和间接光解（1.37倍），然后将UV暴露在2％（v / v）丙酮溶液中作为光敏剂，暴露2 h。这项研究表明，新型纳米载体在保护作物，食品和制药行业的光不稳定化合物方面具有广泛的适用性。

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