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首页> 外文期刊>Journal of Microencapsulation: Microcapsules Liposomes Nanoparticles Microcells Microspheres >Chitosan films incorporated with nettle (Urtica Dioica L.) extract-loaded nanoliposomes: II. Antioxidant activity and release properties
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Chitosan films incorporated with nettle (Urtica Dioica L.) extract-loaded nanoliposomes: II. Antioxidant activity and release properties

机译：掺有荨麻（Urtica Dioica L.）提取物负载的纳米脂质体的壳聚糖薄膜：II.。抗氧化活性和释放性能

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摘要

Chitosan films were loaded with NE nettle (Urtica dioica L.) extract (NE) at concentrations of 0, 0.5, 1 and 1.5%w/w in the free or nanoliposomal form to obtain active and nanoactive films, respectively. The antioxidant potential of the films containing NE-loaded nanoliposomes was decreased in comparison of free NE incorporated films. Diffusion of NE to soybean oil was enough to delay the induction of the oxidation of soybean oil stored for 60 days in contact with chitosan based films. Release studies indicated that the release rate of NE in 95% ethanol simulant significantly decreased by the nanoencapsulation of NE. The diffusion coefficient (D) for chitosan films containing 1.5%w/w of free and encapsulated NE at 25 degrees C was 18.80 and 3.68x10(-7) cm(2)s(-1), respectively. Moreover, the formation of nanoliposomes diminished the increasing effect of temperature on the release rate as when storage temperature increased from 4 degrees C to 40 degrees C.
机译：壳聚糖膜负载有浓度为0、0.5、1和1.5％w / w的NE荨麻提取物（Urtica dioica L.），呈游离或纳米脂质体形式，分别得到活性和纳米活性膜。与掺有游离NE的薄膜相比，含有NE负载的纳米脂质体的薄膜的抗氧化能力降低了。 NE与大豆油的扩散足以延迟与壳聚糖基薄膜接触储存60天的大豆油的氧化诱导。释放研究表明，NE的纳米包封大大降低了NE在95％乙醇模拟物中的释放速率。含1.5％w / w的游离和包封NE的壳聚糖膜在25°C时的扩散系数（D）分别为18.80和3.68x10（-7）cm（2）s（-1）。此外，当储存温度从4摄氏度增加到40摄氏度时，纳米脂质体的形成减弱了温度对释放速率的增加影响。

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