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首页> 外文期刊>Journal of nephrology. >Primary aldosteronism: part II: subtype differentiation and treatment.
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Primary aldosteronism: part II: subtype differentiation and treatment.

机译:原发性醛固酮增多症:第二部分:亚型分化和治疗。

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摘要

After discussing in Part I (Rossi et al, J Nephrol. 2008;21:447-454) the screening strategy to identify the hypertensive patients with primary aldosteronism (PA), we report here an update on the methodology for the further diagnostic work-up and treatment of PA patients. The most common forms of PA are aldosterone-producing adenoma (APA) and adrenocortical hyperplasia (BAH), which are unilateral or bilateral sources of aldosterone excess secretion, respectively. Since APA needs a surgical approach, in contrast to BAH which requires medical treatment, it is crucial to clearly delineate a diagnostic work-up aimed at discriminating the 2 forms. Clinical usefulness and accuracy of adrenal vein sampling, imaging tests (e.g., computed tomography and magnetic resonance) and mineralocorticoid adrenocortical scintigraphy are discussed in detail.
机译:在第I部分(Rossi等,J Nephrol。2008; 21:447-454)中讨论了识别原发性醛固酮增多症(PA)的高血压患者的筛查策略后,我们在此报告了用于进一步诊断工作的方法学的最新进展-和治疗PA患者。 PA的最常见形式是产生醛固酮的腺瘤(APA)和肾上腺皮质增生(BAH),它们分别是醛固酮过量分泌的单边或双边来源。与需要药物治疗的BAH相比,由于APA需要手术方法,因此清楚地描述旨在区分这两种形式的诊断检查至关重要。详细讨论了肾上腺静脉采样,影像学检查(例如计算机断层扫描和磁共振)和盐皮质激素肾上腺闪烁显像的临床实用性和准确性。

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