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首页> 外文期刊>Journal of nephrology. >Hospitalized gastrointestinal bleeding and procedures after renal transplantation in the United States.
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Hospitalized gastrointestinal bleeding and procedures after renal transplantation in the United States.

机译:在美国,肾移植后住院的胃肠道出血和手术程序。

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摘要

The risk of hospitalized gastrointestinal bleeding (GIB) in renal transplant recipients has not been studied in a national renal transplant population. Therefore, 42,906 renal transplant recipients in the United States Renal Data System (USRDS) from 1 July 1994 - 30 June 1998 were analyzed in an historical cohort study of hospitalizations with a primary discharge diagnosis of GIB (ICD9 Code 578.9x) using Cox regression analysis. The 1997 National Hospital Discharge Survey was used to obtain rates of GIB for the general population. Renal transplant recipients had a cumulative incidence of hospitalizations for GIB of 334 events/100,000 person-years. In 1997, compared to the general population, renal transplant recipients had an age-adjusted rate ratio for GIB of 10.69 at one year of follow-up. The strongest risk factors for GIB in Cox regression analysis were graft loss (adjusted hazard ratio, 4.28 (2.84-6.47) and African American recipients who experienced allograft rejection (AHR, 3.04, 95% CI, 1.45-6.37). GIB was associated with increased all-cause mortality (hazard ratio 1.78, 95% CI, 1.39-2.28). GIB is significantly more common in renal transplant recipients than in the general population, and the strongest risk factors are graft loss and African Americans who experience rejection.
机译:尚未在全国肾移植人群中研究肾移植接受者住院胃肠道出血(GIB)的风险。因此,在1994年7月1日至1998年6月30日期间美国肾脏数据系统(USRDS)中的42906名肾移植受者接受了一项历史住院研究,并采用Cox回归分析对原发性GIB进行初步诊断的住院患者进行了分析(ICD9代码578.9x)。 。 1997年全国医院出院调查用于获得一般人群的GIB比率。肾移植接受者的GIB住院累计发病率为334事件/ 100,000人年。在1997年,与普通人群相比,肾移植接受者在随访的第一年中,GIB的年龄调整后比率为10.69。在Cox回归分析中,GIB的最强危险因素是移植物损失(调整后的危险比,4.28(2.84-6.47))和经历同种异体排斥反应的非裔美国人接受者(AHR,3.04,95%CI,1.45-6.37)。增加的全因死亡率(危险比1.78、95%CI,1.39-2.28)GIB在肾移植受者中比在普通人群中更为常见,最主要的危险因素是移植物丢失和遭受排斥的非洲裔美国人。

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