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首页> 外文期刊>Journal of Neurophysiology >Parietal representation of hand velocity in a copy task.
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Parietal representation of hand velocity in a copy task.

机译:在复制任务中手速度的顶视图。

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摘要

We recorded neural activity from ensembles of neurons in areas 5 and 2 of parietal cortex, while two monkeys copied triangles, squares, trapezoids, and inverted triangles and used both linear and nonlinear models to predict the hand velocity from the neural activity of the ensembles. The linear model generally outperformed the nonlinear model, suggesting a reasonably linear relation between the neural activity and the hand velocity. We also found that the average transfer function of the linear model fit to individual cells was a low-pass filter because the neural response had considerable high-frequency power, whereas the hand velocity only had power at frequencies below approximately 5 Hz. Increasing the width of the transfer function, up to a width of 700-800 ms, improved the fit of the model. Furthermore, the Rsqr of the linear model improved monotonically with the number of cells in the ensemble, saturating at 60-80% for a filter width of 700 ms. Finally, it was found that including an interactionterm, which allowed the transfer function to shift with the eye position, did not improve the fit of the model. Thus ensemble neural responses in superior parietal cortex provide a high-fidelity, linear representation of hand kinematics within our task.
机译:我们记录了顶叶皮层5和2区域神经元集合的神经活动,而两只猴子复制了三角形,正方形,梯形和倒三角形,并使用线性和非线性模型从集合的神经活动预测手速。线性模型通常优于非线性模型,这表明神经活动与手速度之间存在合理的线性关系。我们还发现,适合于单个细胞的线性模型的平均传递函数是一个低通滤波器,因为神经反应具有相当大的高频功率,而手部速度仅在低于5 Hz的频率下才具有功率。将传递函数的宽度增加到700-800 ms的宽度,可以改善模型的拟合度。此外,线性模型的Rsqr随着整体中单元数量的增加而单调提高,对于700 ms的滤波器宽度,其饱和度达到60-80%。最后,发现包括交互项(允许传递函数随眼睛位置移动)并不能改善模型的拟合度。因此,上顶皮质的整体神经反应在我们的任务中提供了手运动学的高保真线性表示。

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