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Optimization of Photoreaction For the Production of Vitamin D2

机译:用于生产维生素D2的光反应的优化

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摘要

The photochemical formation of vitamin D2(VD2)is complicated,and optimization is essential for commercial production.An optimization methodology is introduced for investigating the factors influencing highly effective production of VD2.For this research,the irradiation time and the initial concentration of ergo-sterol(C_E)were fully considered as the significant factors to simulate in the predictive models developed using SPSS and MATLAB software.The data obtained from the designed experiments were fit as two variable equations and their relationships were plotted as three-dimensional surfaces.The model has a quite satisfactory coefficient(R2>0.99).The best conditions observed were:C_E=1.09 g/dm3 and an irradiation time of 64.5 min,while the yield of pre-vitamin D2(P)reached a maximum of 45.83%.Three experiments were performed and an average yield 45.93% was obtained.The yield obtained could be compared with the predicted yield satisfactorily.
机译:维生素D2(VD2)的光化学形成很复杂,优化对商业化生产是必不可少的。引入了一种优化方法,以研究影响VD2高效生产的因素。在使用SPSS和MATLAB软件开发的预测模型中,将甾醇(C_E)充分考虑作为要模拟的重要因素,将设计实验获得的数据拟合为两个变量方程,并将它们之间的关系绘制为三维表面。维生素C的最佳系数为(R2> 0.99),最佳条件为C_E = 1.09 g / dm3,辐照时间为64.5 min,维生素D2(P)的最高产量为45.83%.3进行了实验,平均收率为45.93%。所得收率可与预期收率比较。

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