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首页> 外文期刊>Journal of Neurophysiology >Discharge of the readily releasable pool with action potentials at hippocampal synapses.
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Discharge of the readily releasable pool with action potentials at hippocampal synapses.

机译：释放易于释放的池，在海马突触处具有动作电位。

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A readily releasable pool (RRP) of synaptic vesicles has been identified at hippocampal synapses with application of hypertonic solution. RRP size correlates with important properties of synaptic function such as release probability. However, a discrepancy in RRP size has been reported depending on the method used to evoke synaptic release. This study was undertaken to determine quantitative relationships between the RRP defined with hypertonic solution and that released with trains of action potentials. We find that asynchronous release at cell culture synapses contributes significantly to the discharge of the RRP with trains of action potentials and that RRP size is the same when elicited by either nerve stimuli or hypertonic challenge.
机译：通过应用高渗溶液，在海马突触处发现了一个易于释放的突触囊泡池（RRP）。 RRP大小与突触功能的重要属性（例如释放概率）相关。但是，已报告了RRP大小的差异，具体取决于引起突触释放的方法。进行这项研究来确定高渗溶液定义的RRP与动作电位序列释放的RRP之间的定量关系。我们发现，在细胞培养突触处的异步释放显着促进了具有一系列动作电位的RRP的释放，并且当神经刺激或高渗刺激引起RRP大小相同。

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