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首页> 外文期刊>Journal of Neurophysiology >Effect of contralateral pure tone stimulation on distortion emissions suggests a frequency-specific functioning of the efferent cochlear control.
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Effect of contralateral pure tone stimulation on distortion emissions suggests a frequency-specific functioning of the efferent cochlear control.

机译：对侧纯音刺激对失真发射的影响表明耳蜗传出控制的特定频率功能。

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摘要

Contralateral acoustic stimulation (CAS) with white noise and pure tone stimuli was used to assess frequency specificity of efferent olivocochlear control of cochlear mechanics in the gerbil. Changes of the cochlear amplifier can be monitored by distortion product otoacoustic emissions (DPOAEs), which are a byproduct of the nonlinear amplification by the outer hair cells. We used the quadratic DPOAE f2-f1 as ipsilateral probe, as it is known to be sensitive to efferent olivocochlear activity. White noise CAS, used to evoke efferent activity, had maximal effects on the DPOAE level for f2-stimulus frequencies of 5-7 kHz. The dominant effect during CAS was a DPOAE level increase of up to 13.5 dB. The frequency specificity of the olivocochlear system was evaluated by presenting pure tones (0.5-38 kHz) as contralateral stimuli to evoke efferent activity. Maximal DPOAE level changes were triggered by CAS frequencies close to the frequency of the DPOAE elicitor tones (tested f2 range: 2.5-15 kHz). The effective CAS frequency range covered 1.4-2.4 octaves and was centered 0.42 octaves below the DPOAE elicitor tone f2. The frequency-specific effect of CAS with pure tones suggests a dedicated central control of mechanical adjustments for peripheral frequency processing.
机译：对侧声学刺激（CAS）具有白噪声和纯音刺激用于评估沙鼠耳蜗力学传出的小耳蜗控制的频率特异性。耳蜗放大器的变化可以通过失真产物耳声发射（DPOAE）进行监视，该失真产物是外毛细胞进行非线性放大的副产物。我们使用二次DPOAE f2-f1作为同侧探针，因为它已知对传出的小核糖核酸活性敏感。用于唤起传出活动的白噪声CAS对5-7 kHz的f2刺激频率对DPOAE水平具有最大影响。 CAS期间的主要作用是DPOAE的水平增加高达13.5 dB。通过呈现纯音（0.5-38 kHz）作为对侧刺激来唤起传出活动，来评估少毛耳系统的频率特异性。 CAS频率接近DPOAE激发子音调的频率（测试的f2范围：2.5-15 kHz）触发了最大DPOAE电平变化。有效的CAS频率范围覆盖1.4-2.4个八度，并位于DPOAE激发音f2下方0.42个八度的中心。 CAS具有纯音的特定于频率的效果建议对外围频率处理进行机械调整的专用中央控制。

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