...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Biophysical Chemistry: An International Journal Devoted to the Physical Chemistry of Biological Phenomena >Electromigration of polyion homopolymers across biomembranes: a biophysical model
【24h】

Electromigration of polyion homopolymers across biomembranes: a biophysical model

机译：聚离子均聚物跨生物膜的电迁移：生物物理模型

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The analysis of polyion transmembrane translocation was performed using membrane electrical equivalent circuit. The dependence of polyion flux across membranes on time, membrane electrical conductance, membrane electrical capacitance, degree of polymerization, water solution conductance and applied transmembrane potential is discussed. The changes in polyion flux were up to 88% after 1 ms. Both the increase of polyion chain length and the decrease of membrane conductance resulted in the diminution of this effect. Inversion of flux direction was observed as a result of external potential changes. Reversal curves, representing the values of considered parameters for zero-flux were also shown. The replacement of a polyanion by a polycation of the same chain length resulted in the same shape of the surface plot but with opposite orientation. The analysis describes the effect of transmembrane potential on the translocation rate of polyanionic polysialic acid and polynucleotides, and polycationic peptides across membranes. (C) 2000 Elsevier Science B.V. All rights reserved. [References: 32]
机译：使用膜等效电路对聚离子跨膜移位进行分析。讨论了跨膜的聚离子通量对时间，膜电导率，膜电容，聚合度，水溶液电导率和施加的跨膜电势的依赖性。 1毫秒后，聚离子通量的变化高达88％。聚离子链长度的增加和膜电导的降低都导致这种作用的减弱。由于外部电势变化，观察到磁通方向反转。还显示了代表零通量考虑参数值的反向曲线。用相同链长的聚阳离子取代聚阴离子可得到相同形状的表面图，但方向相反。该分析描述了跨膜电位对聚阴离子聚唾液酸和多核苷酸以及跨膜的聚阳离子肽的转运速率的影响。 （C）2000 Elsevier Science B.V.保留所有权利。 [参考：32]

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号