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首页> 外文期刊>Journal of Neurophysiology >Recording from the same neurons chronically in motor cortex.
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Recording from the same neurons chronically in motor cortex.

机译：长期从运动皮层中的相同神经元进行记录。

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摘要

Two rhesus monkeys were implanted with silicon arrays of 96 microelectrodes. Neural activity was recorded periodically over a period of weeks to months. We have developed a method to determine whether single units in two separate recording sessions represent the same neuron. Pairwise cross-correlograms, the autocorrelogram, waveform shape, and mean firing rate were used together as identifying features of a neuron. When two units recorded on separate days were compared using these features, their similarity scores tended to be either high, indicating two recordings from the same neuron, or low, indicating different neurons. Although these metrics are individually weak, together they produce a strong classifier. Some neurons were recorded for >100 days. These monkeys performed a center-out reaching task, and we found that the firing properties of chronically recorded neurons were stable over time.
机译：两只恒河猴植入了96个微电极的硅阵列。在数周至数月的时间内定期记录神经活动。我们已经开发出一种方法来确定两个单独的记录会话中的单个单元是否代表相同的神经元。成对的交叉相关图，自相关图，波形形状和平均激发速率一起用作神经元的识别特征。当使用这些功能对在不同日期记录的两个单位进行比较时，它们的相似性得分趋向于较高（表示来自同一神经元的两个记录）或较低（表示不同的神经元）。尽管这些指标各自较弱，但它们共同产生了强大的分类器。记录了一些神经元持续100天以上。这些猴子执行了中心伸出的任务，我们发现长期记录的神经元的放电特性随时间稳定。

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