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首页> 外文期刊>Journal of Neurophysiology >Contribution of sensory feedback to the generation of extensor activity during walking in the decerebrate Cat.
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Contribution of sensory feedback to the generation of extensor activity during walking in the decerebrate Cat.

机译：在去大脑的猫中行走时，感觉反馈对伸肌活动产生的贡献。

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摘要

In this investigation we have estimated the afferent contribution to the generation of activity in the knee and ankle extensor muscles during walking in decerebrate cats by loading and unloading extensor muscles, and by unilateral deafferentation of a hind leg. The total contribution of afferent feedback to extensor burst generation was estimated by allowing one hind leg to step into a hole in the treadmill belt on which the animal was walking. In the absence of ground support the level of activity in knee and ankle extensor muscles was reduced to approximately 70% of normal. Activity in the ankle extensors could be restored during the "foot-in-hole" trials by selectively resisting extension at the ankle. Thus feedback from proprioceptors in the ankle extensor muscles probably makes a large contribution to burst generation in these muscles during weight-bearing steps. Similarly, feedback from proprioceptors in knee extensor appears to contribute substantially to the activation of knee extensor muscles because unloading and loading these muscles, by lifting and dropping the hindquarters, strongly reduced and increased, respectively, the level of activity in the knee extensors. This conclusion was supported by the finding that partial deafferentation of one hind leg by transection of the L4-L6 dorsal roots reduced the level of activity in the knee extensors by approximately 50%, but did not noticeably influence the activity in ankle extensor muscles. However, extending the deafferentation to include the L7-S2 dorsal roots decreased the ankle extensor activity. We conclude that afferent feedback contributes to more than one-half of the input to knee and ankle extensor motoneurons during the stance phase of walking in decerebrate cats. The continuous contribution of afferent feedback to the generation of extensor activity could function to automatically adjust the intensity of activity to meet external demands.
机译：在这项调查中，我们估计了通过加载和卸载伸肌以及后肢单侧脱除力，在去脑猫中行走时，对膝盖和踝伸肌活动产生的贡献。通过让一只后腿踏入动物在其上行走的跑步机皮带上的一个孔，估计传入反馈对伸肌爆发产生的总贡献。在没有地面支撑的情况下，膝盖和脚踝伸肌的活动水平降低到正常水平的约70％。可以通过有选择地抵抗脚踝的伸展来恢复脚踝伸肌的活动。因此，来自脚踝伸肌中本体感受器的反馈可能在负重步骤中对这些肌肉中爆发的产生做出了很大贡献。类似地，来自膝盖伸肌的本体感受器的反馈似乎对膝盖伸肌的激活有实质性的贡献，因为通过举起和放下后肢来卸载和加载这些肌肉，分别会大大降低和增加膝盖伸肌的活动水平。这一结论得到了以下发现的支持：通过横切L4-L6背根使一只后腿部分脱除咖啡因会使膝部伸肌的活动水平降低约50％，但并未显着影响踝伸肌的活动。但是，将脱除咖啡因的范围扩大到包括L7-S2背根会降低踝关节伸肌的活动。我们得出的结论是，在无脑猫行走的站立阶段，传入反馈对膝盖和脚踝伸肌神经元输入的贡献超过一半。传入反馈对伸肌活动的持续贡献可以起到自动调节活动强度以满足外部需求的作用。

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