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首页> 外文期刊>Journal of Neuroscience Methods >Transvenous versus perinervous stimulation of the phrenic nerve to assess the diaphragmatic strength in rabbits.
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Transvenous versus perinervous stimulation of the phrenic nerve to assess the diaphragmatic strength in rabbits.

机译：神经的经静脉与神经周围刺激，以评估兔的the肌力量。

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摘要

Diaphragmatic strength can be measured by transdiaphragmatic pressure during phrenic nerve stimulation. In order to avoid phrenic nerve dissection, a transjugular approach of the phrenic nerve can be performed. The objective of this study was to verify the identity of perinervous and transvenous techniques of phrenic nerve stimulation to assess diaphragmatic force. In intact (n = 9) or right phrenicotomized (n = 12) rabbits, we compared esophageal pressure (Peso) induced by supramaximal perinervous stimulation of the phrenic nerve with that obtained by transvenous stimulation of the phrenic nerve. Electromyography (EMG) of the thoracic muscles was studied in four animals. We found no difference between Peso induced by perinervous (PNS) and transvenous (TVS) unilateral or bilateral phrenic nerve stimulation. During unilateral stimulation, no EMG activity was recorded in the non stimulated diaphragm, or in the middle part of the esophagus, or in ipsi- and contralateral accessory inspiratory muscles. We conclude that in rabbits, unilateral or bilateral TVS of the phrenic nerve is functionally equivalent to PNS, whatever the side of stimulation; Peso is not altered by esophageal contraction in TVS. Transvenous stimulation can replace perinervous stimulation in experimental studies, when cervical access is difficult.
机译：横strength肌强度可以通过nerve神经刺激期间的横dia肌压力来测量。为了避免神经解剖，可以进行ju神经的经颈静脉入路。这项研究的目的是验证the神经刺激的围神经和经静脉技术以评估diaphragm肌力的身份。在完整（n = 9）或右肾切开术（n = 12）的兔子中，我们比较了经最大神经per神经刺激引起的食管压力（Peso）与经静脉刺激stimulation神经获得的食管压力（Peso）。在四只动物中研究了胸肌的肌电图（EMG）。我们发现，经会阴（PNS）和经静脉（TVS）单侧或双侧神经刺激引起的比索之间没有差异。在单侧刺激过程中，未刺激的diaphragm肌，食道中部或同侧和对侧副吸肌均未记录到EMG活动。我们得出的结论是，在兔子中，无论刺激的一面如何，the神经的单侧或双侧TVS在功能上均与PNS等效。在TVS中，食管收缩不会改变比索。在难以进入宫颈的实验研究中，静脉刺激可以代替神经刺激。

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