...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Neuroscience Methods >A Windows software package to record from voltage-clamped Xenopus oocytes.
【24h】

A Windows software package to record from voltage-clamped Xenopus oocytes.

机译：Windows软件包，用于记录电压钳制的非洲爪蟾卵母细胞。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

We have written a software package to record, display and analyze membrane currents elicited by neurotransmitter receptors or voltage-activated channels in voltage-clamped Xenopus oocytes. This suite, which consists of 4 applications, runs on IBM-PC compatible microcomputers under Windows 3.1. The recording programs use Direct Memory Access (DMA) to access the analog-digital board. The first program, NicPulse, is aimed at studying voltage-activated channels. It delivers voltage steps to the voltage-clamp and records the resulting membrane current. The second program, NicScope, emulates a dual-trace digital oscilloscope. It operates either in continuous or triggered mode, and is used chiefly to display neurotransmitter-induced responses in oocytes. The third recording program, VRamp, automatically determines the voltage-current relationship of drug-activated responses (I/V curve), by applying a voltage ramp and recording the subsequent clamping current. The last program, NicView, is designed to analyze records taken with NicScope and NicPulse. The present paper will discuss several issues regarding the design of these programs, and will give a brief description of each application.
机译：我们已经编写了一个软件包，用于记录，显示和分析由电压传导的爪蟾卵母细胞中的神经递质受体或电压激活的通道引起的膜电流。该套件由4个应用程序组成，可在Windows 3.1下与IBM-PC兼容的微型计算机上运行。记录程序使用直接内存访问（DMA）访问模拟数字板。第一个程序NicPulse旨在研究电压激活的通道。它将电压阶跃传递到电压钳并记录产生的膜电流。第二个程序NicScope模拟了双轨迹数字示波器。它以连续或触发模式运行，主要用于显示卵母细胞中神经递质诱导的反应。第三个记录程序VRamp通过施加电压斜坡并记录随后的钳位电流来自动确定药物激活的响应的电压-电流关系（I / V曲线）。最后一个程序NicView用于分析使用NicScope和NicPulse拍摄的记录。本文将讨论有关这些程序设计的几个问题，并将对每个应用程序进行简要说明。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号