首页> 外文期刊>Biophysical Chemistry: An International Journal Devoted to the Physical Chemistry of Biological Phenomena >Viscosity B-coefficients and standard partial molar volumes of amino acids, and their roles in interpreting the protein (enzyme) stabilization.
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Viscosity B-coefficients and standard partial molar volumes of amino acids, and their roles in interpreting the protein (enzyme) stabilization.

机译:氨基酸的粘度B系数和标准偏摩尔体积,以及它们在解释蛋白质(酶)稳定作用中的作用。

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摘要

This review systematically surveys the viscosity B-coefficients and standard partial molar volumes of amino acids at various temperatures as these data are quite important for interpreting the hydration and other properties of peptides and proteins. The effect of organic solutes and various ions on the viscometric and volumetric properties of amino acids has also been discussed in terms of their kosmotropic ('structure-making') effects on the hydration of amino acids. The comparison of these effects on the amino acid hydration enables us to have a better understanding of the influence of organic solute and salt on the protein stabilization. In addition, the viscometric and volumetric behaviors of amino acid ions (cations and anions) are also summarized because these ions have recently been incorporated as part of novel ionic liquids, which have wide applications in biocatalysis and protein stabilization.
机译:这篇综述系统地考察了在各种温度下氨基酸的粘度B系数和标准的部分摩尔体积,因为这些数据对于解释肽和蛋白质的水合和其他性质非常重要。还讨论了有机溶质和各种离子对氨基酸的粘度和体积特性的影响,涉及它们对氨基酸水合的同质(“结构制造”)影响。这些对氨基酸水合作用的比较使我们能够更好地理解有机溶质和盐对蛋白质稳定性的影响。此外,还总结了氨基酸离子(阳离子和阴离子)的粘度和体积行为,因为这些离子最近已作为新型离子液体的一部分被纳入,这些离子液体在生物催化和蛋白质稳定化中具有广泛的应用。

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