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首页> 外文期刊>Journal of Neuroscience Methods >Shape, connectedness and dynamics in neuronal networks
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Shape, connectedness and dynamics in neuronal networks

机译:神经元网络的形状,连接性和动力学

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摘要

The morphology of neurons is directly related to several aspects of the nervous system, including its connectedness, health, development, evolution, dynamics and, ultimately, behavior. Such interplays of the neuronal morphology can be understood within the more general shape-function paradigm. The current article reviews, in an introductory way, some key issues regarding the role of neuronal morphology in the nervous system, with emphasis on works developed in the authors' group. The following topics are addressed: (a) characterization of neuronal shape; (b) stochastic synthesis of neurons and neuronal systems; (c) characterization of the connectivity of neuronal networks by using complex networks concepts; and (d) investigations of influences of neuronal shape on network dynamics. The presented concepts and methods are useful also for several other multiple object systems, such as protein-protein interaction, tissues, aggregates and polymers.
机译:神经元的形态与神经系统的多个方面直接相关,包括其连接性,健康性,发育,进化,动力学以及最终的行为。神经元形态的这种相互作用可以在更一般的形状功能范例中理解。本文以介绍性的方式回顾了有关神经元形态在神经系统中的作用的一些关键问题,并着重介绍了作者小组的研究成果。涉及以下主题:(a)神经元形状的表征; (b)神经元和神经元系统的随机合成; (c)通过使用复杂的网络概念来表征神经网络的连通性; (d)研究神经元形状对网络动力学的影响。提出的概念和方法也可用于其他几种多目标系统,例如蛋白质-蛋白质相互作用,组织,聚集体和聚合物。

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