首页> 外文期刊>Journal of Neuroscience Methods >Visualization of spiral ganglion neurites within the scala tympani with a cochlear implant in situ.
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Visualization of spiral ganglion neurites within the scala tympani with a cochlear implant in situ.

机译:人工耳蜗植入时,在鼓ala内显示螺旋神经节神经突。

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摘要

Current cochlear histology methods do not allow in situ processing of cochlear implants. The metal components of the implant preclude standard embedding and mid-modiolar sectioning, and whole mounts do not have the spatial resolution needed to view the implant within the scala tympani. One focus of recent auditory research is the regeneration of structures within the cochlea, particularly the ganglion cells and their processes, and there are multiple potential benefits to cochlear implant users from this work. To facilitate experimental investigations of auditory nerve regeneration performed in conjunction with cochlear implantation, it is critical to visualize the cochlear tissue and the implant together to determine if the nerve has made contact with the implant. This paper presents a novel histological technique that enables simultaneous visualization of the in situ cochlear implant and neurofilament-labeled nerve processes within the scala tympani, and the spatial relationship between them.
机译:当前的人工耳蜗组织学方法不允许原位处理人工耳蜗。植入物的金属成分无法进行标准的埋入和mo中切面,并且整个安装座都没有必要的空间分辨率来查看在鼓ala中的植入物。最近的听觉研究的焦点之一是耳蜗内结构的再生,特别是神经节细胞及其过程,并且这项工作为人工耳蜗植入用户带来了许多潜在的好处。为了促进与耳蜗植入一起进行的听觉神经再生的实验研究,至关重要的是将耳蜗组织和植入物一起可视化,以确定神经是否已经与植入物接触。本文介绍了一种新颖的组织学技术,可以同时可视化耳蜗内的原位人工耳蜗和神经丝标记的神经过程,以及它们之间的空间关系。

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