A surgical technique of spinal cord cell transplantation in amyotrophic lateral sclerosis.

Blanquer M; Perez Espejo MA; Martinez Lage JF; Iniesta F; Martinez S; Moraleda JM

首页> 外文期刊>Journal of Neuroscience Methods >A surgical technique of spinal cord cell transplantation in amyotrophic lateral sclerosis.

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A surgical technique of spinal cord cell transplantation in amyotrophic lateral sclerosis.

机译：肌萎缩性侧索硬化症的脊髓细胞移植手术技术。

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We report an original method for implanting bone marrow stem cells within the spinal cord parenchyma. This method was used for the experimental treatment of patients diagnosed with amyotrophic lateral sclerosis. The methodology is reproducible and devoid of major complications even in patients showing significant spinal atrophy. Therefore, this report describes a surgical procedure that could be used in other experimental treatments involving the intraspinal delivery of stem cells.

机译：我们报告原始方法植入骨髓实质细胞内脊髓实质。该方法用于实验诊断为肌萎缩性侧索硬化的患者。该方法是可重现的，即使在显示出明显的脊髓萎缩的患者中也没有重大并发症。因此，本报告描述了一种外科手术程序，可用于涉及干细胞脊柱内递送的其他实验治疗。

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《Journal of Neuroscience Methods》 |2010年第2期|共3页
作者
Blanquer M; Perez Espejo MA; Martinez Lage JF; Iniesta F; Martinez S; Moraleda JM;
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正文语种 eng
中图分类神经病学与精神病学;
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1. A surgical technique of spinal cord cell transplantation in amyotrophic lateral sclerosis. [J] . Blanquer M, Perez Espejo MA, Martinez Lage JF, Journal of Neuroscience Methods . 2010,第2期

机译：肌萎缩性侧索硬化症的脊髓细胞移植手术技术。
2. Glial cells of the spinal cord and subcortical white matter up-regulate neuronal nitric oxide synthase in sporadic amyotrophic lateral sclerosis. [J] . Anneser JM, Cookson MR, Ince PG, Experimental Neurology . 2001,第2期

机译：脊髓的胶质细胞和皮质下白质在散发性肌萎缩性侧索硬化症中上调神经元一氧化氮合酶。
3. Expression of glial cell line-derived growth factor mRNA in the spinal cord and muscle in amyotrophic lateral sclerosis. [J] . Yamamoto M, Sobue G, Yamamoto K, Neuroscience Letters: An International Multidisciplinary Journal Devoted to the Rapid Publication of Basic Research in the Brain Sciences . 1996,第1a2期

机译：胶质细胞源性生长因子mRNA在肌萎缩性侧索硬化症的脊髓和肌肉中的表达。
4. FDG-PET and the Assessment of Spinal Cord Metabolism in Amyotrophic Lateral Sclerosis (ALS) [C] . Anna Maria Massone, Cristina Campi, Mauro C. Beltrametti, IEEE Nuclear Science Symposium . 2016

机译：FDG-PET和肌营养侧面硬化症（ALS）中脊髓代谢的评估
5. Effect of Ephrin-B3 on the Survival of Adult Rat Spinal Cord Derived Neural Stem/Progenitor Cells In Vitro and After Transplantation into the Injured Rat Spinal Cord. [D] . Fan, Xin Yan Susan. 2012

机译：Ephrin-B3对成年大鼠脊髓源性神经干/祖细胞的体外存活以及移植到受损大鼠脊髓后的存活率的影响。
6. High signal intensity on T1 weighted MRI of the anterolateral column of the spinal cord in amyotrophic lateral sclerosis. [O] . M Waragai, H Shinotoh, M Hayashi, 1997

机译：肌萎缩性侧索硬化症脊髓前外侧柱的T1加权MRI上的高信号强度。
7. A surgical technique of spinal cord cell transplantation in amyotrophic lateral sclerosis [O] . Blanquer, Miguel, Pérez-Espejo, Miguel Ángel, Martínez-Lage, Juan F., 2010

机译：肌萎缩性侧索硬化症的脊髓细胞移植手术技术

A surgical technique of spinal cord cell transplantation in amyotrophic lateral sclerosis.

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