...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Biophysical Chemistry: An International Journal Devoted to the Physical Chemistry of Biological Phenomena >Raman spectroscopic investigation on the interaction of malignant hepatocytes with doxorubicin.
【24h】

Raman spectroscopic investigation on the interaction of malignant hepatocytes with doxorubicin.

机译：拉曼光谱研究恶性肝细胞与阿霉素的相互作用。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Raman spectroscopy has proven to be a very powerful technique and is currently experiencing a renaissance. In this paper, it is used to explore the interaction between doxorubicin and malignant hepatocytes in vitro. For the addition of doxorubicin, the band intensity at 1609 cm-1, mainly assigned to C=C in-plane bending mode of phenylalanine and/or tyrosine residues, increases significantly, and the intensities of the bands at 1585 and 1313 cm-1, mainly due to the guanine bases, decrease greatly. In addition, Raman spectra are investigated at different doxorubicin concentrations, and the mean areas ratios of the band at 1450 to that at 1003 cm-1, A1450/A1003, fluctuate according to the doxorubicin concentration increasing, which suggests that doxorubicin affects the relative content of lipid in cells.
机译：拉曼光谱已被证明是一种非常强大的技术，目前正在复兴。本文用于探讨阿霉素与恶性肝细胞之间的相互作用。对于添加阿霉素，1609 cm-1处的谱带强度（主要分配给苯丙氨酸和/或酪氨酸残基的C = C平面内弯曲模式）显着增加，并且1585和1313 cm-1处的谱带强度，主要由于鸟嘌呤碱基，大大减少。此外，研究了在不同阿霉素浓度下的拉曼光谱，并且随着阿霉素浓度的增加，在1450与1003 cm-1处的能带平均面积比（A1450 / A1003）会波动，这表明阿霉素会影响相对含量细胞中的脂质。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号