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Cryotherapy and high intensity focused ultrasound for prostate cancer

机译:冷冻疗法和高强度聚焦超声治疗前列腺癌

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Men with prostate cancer and their healthcare professionals are faced with several options for treating the primary tumour at the time of diagnosis and any recurrence. Newer treatments such as cryotherapy and high intensity focused ultrasound are available in some centres in the UK and have enthusiastic advocates. In 2005, the National Institute for Health and Clinical Excellence (NICE) issued guidance on cryotherapy and ultrasound treatment saying that "the current evidence on efficacy and safety" seemed "adequate to support their use" in patients with prostate cancer. But in 2008, NICE published clinical guidelines on prostate cancer which stated that these treatments "are not recommended for men with localised prostate cancer other than in the context of controlled clinical trials comparing their use with established interventions." This apparent change of heart caused concern among urologists and even reached the national press. However, the advice was not really inconsistent-NICE deemed these techniques safe and efficacious enough to be used but thought that the evidence on their clinical effectiveness compared with alternatives was insufficient to recommend their routine use in the NHS.
机译:患有前列腺癌的男性及其医疗保健专业人员在诊断和任何复发时都面临多种治疗原发性肿瘤的选择。英国的一些中心提供了诸如冷冻疗法和高强度聚焦超声之类的较新疗法,并且有热情的拥护者。 2005年,美国国家卫生与临床卓越研究所(NICE)发布了有关冷冻疗法和超声治疗的指南,称“有关功效和安全性的最新证据”似乎“足以支持其在前列腺癌患者中的使用”。但是在2008年,NICE发布了有关前列腺癌的临床指南,该指南指出“除了在将其使用与既定干预措施进行比较的对照临床试验的背景下,不建议对局限性前列腺癌的男性使用这些治疗方法”。这种明显的心脏变化引起了泌尿科医师的关注,甚至引起了全国新闻界的关注。但是,建议并非真的不一致-NICE认为这些技术足够安全有效,可以使用,但认为与替代品相比其临床有效性的证据不足以推荐其在NHS中的常规使用。

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