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首页> 外文期刊>Journal of obstetrics and gynaecology: the journal of the Institute of Obstetrics and Gynaecology >The accuracy of risk scores in predicting preterm birth--a systematic review.
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The accuracy of risk scores in predicting preterm birth--a systematic review.

机译:风险评分在预测早产中的准确性-系统评价。

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This review aims to determine the accuracy with which published risk scores predict spontaneous preterm birth in pregnant women. Studies were identified without language restrictions through nine different databases (up to June 2002), and manual searching of bibliographies of known primary and review articles. Two reviewers selected studies independently and extracted data on their characteristics, quality and accuracy. Accuracy data were used to form 2 x 2 contingency tables of the results of risk scoring with spontaneous preterm birth as the reference standard. Heterogeneity was assessed and its reasons were explored. Summary estimates of accuracy were produced within clinically appropriate subgroups. There were 19 primary accuracy articles that met the selection criteria, including a total of 67 390 women. There are 12 different risk-scoring systems, the one developed by Creasy being the most commonly evaluated. Quality features of an ideal study, such as blinding and consecutive enrolment, were frequently missing from the included studies, no study fulfilled all criteria for high quality study, and there was heterogeneity between their accuracy estimates. The reference standard most often used was birth before 37 weeks' gestation. The point estimates for the likelihood ratios (LRs) varied widely among the studies. LRs for an abnormal score (LR + ) ranged from 1.0 (95% confidence interval (CI) 0.6 - 1.4) to 38.8 (95% CI 23.5 - 63.9) while that for a normal score (LR-) ranged from 0.1 (95% CI 0.02 - 0.6) to 1.2 (95% CI 0.9 - 1.6). In otherwise asymptomatic women, risk scoring in early pregnancy has a wide range of accuracy in predicting spontaneous preterm birth before 37 weeks' gestation. The evidence is of a relatively poor quality and lacks clinically important reference standards.
机译:这篇综述旨在确定已发表的风险评分预测孕妇自发性早产的准确性。通过九个不同的数据库(截止到2002年6月),并手动搜索已知的主要文章和评论文章的书目来确定研究不受语言限制。两名审稿人独立选择研究并提取其特征,质量和准确性的数据。以准确性数据形成自发性早产为参考标准的风险评分结果的2 x 2列联表。评估了异质性并探讨了其原因。在临床上适当的亚组内产生了准确性的简要估算。有19篇符合选择标准的基本准确性文章,包括67 390名女性。共有12种不同的风险评分系统,其中最容易评估的是Creasy开发的系统。理想研究的质量特征(例如盲法和连续入学)经常从所包括的研究中缺失,没有一项研究能够满足高质量研究的所有标准,并且其准确性评估之间存在异质性。最常用的参考标准是在妊娠37周之前出生。在这些研究中,似然比(LRs)的点估计差异很大。异常评分(LR +)的LR范围为1.0(95%置信区间(CI)0.6-1.4)至38.8(95%CI 23.5-63.9),而正常评分(LR-)的LRs为0.1(95%) CI 0.02-0.6)至1.2(95%CI 0.9-1.6)。在其他无症状的妇女中,怀孕初期的风险评分在预测妊娠37周之前的自然早产方面具有广泛的准确性。证据质量相对较差,缺乏临床上重要的参考标准。

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