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首页> 外文期刊>Journal of occupational and environmental medicine >Relationship between welding fume concentration and systemic inflammation after controlled exposure of human subjects with welding fumes from metal inert gas brazing of zinc-coated materials
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Relationship between welding fume concentration and systemic inflammation after controlled exposure of human subjects with welding fumes from metal inert gas brazing of zinc-coated materials

机译：人体受锌涂层材料的金属惰性气体钎焊产生的焊接烟尘控制接触后，焊接烟尘浓度与全身炎症的关系

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OBJECTIVES:: It has been shown that exposure of subjects to emissions from a metal inert gas (MIG) brazing process of zinc-coated material led to an increase of high-sensitivity C-reactive protein (hsCRP) in the blood. In this study, the no-observed-effect level (NOEL) for such emissions was assessed. METHODS:: Twelve healthy subjects were exposed for 6 hours to different concentrations of MIG brazing fumes under controlled conditions. High-sensitivity C-reactive protein was measured in the blood. RESULTS:: For welding fumes containing 1.20 and 1.50 mg m zinc, high-sensitivity C-reactive protein was increased the day after exposure. For 0.90 mg m zinc, no increase was detected. CONCLUSIONS:: These data indicate that the no-observed-effect level for emissions from a MIG brazing process of zinc-coated material in respect to systemic inflammation is found for welding fumes with zinc concentrations between 0.90 and 1.20 mg m.
机译：目的：已经表明，受试者暴露于镀锌材料的金属惰性气体（MIG）钎焊过程中产生的排放物会导致血液中高敏C反应蛋白（hsCRP）的增加。在这项研究中，评估了此类排放的无观测影响水平（NOEL）。方法：在受控条件下，将十二名健康受试者暴露于不同浓度的MIG钎焊烟气中6小时。在血液中测量了高敏感性C反应蛋白。结果：对于含1.20和1.50 mg m锌的焊接烟气，暴露后第二天增加了高敏感性C反应蛋白。对于0.90 mg m的锌，未检测到增加。结论：这些数据表明，对于锌浓度为0.90至1.20 mg m的焊接烟尘，发现了MIG钎焊镀锌材料的MIG钎焊过程中与全身炎症无关的排放水平。

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