Management of treatment with direct-acting antiviral (DAA) in clinical practice.

Thierry Fontanges

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Management of treatment with direct-acting antiviral (DAA) in clinical practice.

机译：在临床实践中使用直接作用抗病毒药物（DAA）进行治疗管理。

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The triple therapy has brought about a genuine revolution in the care of patients with chronic hepatitis C virus infection, although achieving a high cure rate requires adding disciplines beyond the attending physician when confronted by a motivated patient. The treatment is complex because of the many parameters involved (such as fibrosis score, patient's history of previous antiviral treatment and viral kinetics during treatment). A working knowledge of drug interactions and contraindications for drugs other than antiviral therapy is required, as well as meticulous follow-up.

机译：三重疗法为慢性丙型肝炎病毒感染患者的护理带来了一场真正的革命，尽管要达到高治愈率，需要有积极进取的患者时，除了主治医师之外还需要增加其他学科。由于涉及许多参数（例如纤维化评分，患者先前的抗病毒治疗史以及治疗期间的病毒动力学），因此治疗非常复杂。除抗病毒治疗外，还需要有关药物相互作用和禁忌症的工作知识，以及细致的随访。

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《Clinics and research in hepatology and gastroenterology》 |2011年第2期|共5页
作者
Thierry Fontanges;
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正文语种 eng
中图分类消化系及腹部疾病;
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1. Management of treatment with direct-acting antiviral (DAA) in clinical practice. [J] . Thierry Fontanges Clinics and research in hepatology and gastroenterology . 2011,第Suppla2期

机译：在临床实践中使用直接作用抗病毒药物（DAA）进行治疗管理。
2. Changes in the use of direct acting antiviral(s) (DAA) in the treatment of chronic hepatitis C (CHC) patients in clinical practice. HERACLIS: a Hellenic multicenter real-life cohort clinical study [J] . Papatheodoridis George V., Koskinas John, Goulis Ioannis, Hepatology: Official Journal of the American Association for the Study of Liver Diseases . 2017,第Suppla1期

机译：直接作用抗病毒（DAA）在临床实践中治疗慢性丙型肝炎患者的使用变化。 Heraclis：Hellenic MultiCenter现实生活队列临床研究
3. Efficacy and safety of the currently recommended regimens with direct acting antiviral(s) (DAA) in the treatment of chronic hepatitis C (CHC) patients in clinical practice. A Greek multicenter real-life cohort study. [J] . Papatheodoridis George V., Kapatais Andreas, Goulis Ioannis, Hepatology: Official Journal of the American Association for the Study of Liver Diseases . 2016,第S1期

机译：目前推荐方案的疗效和安全性与直接作用抗病毒（DAA）治疗临床实践中慢性丙型肝炎患者的抗性抗病毒（DAA）。希腊多中心现实生活队列研究。
4. Early and long term clinical outcomes from the treatment of proximal LAD stenoses with drug-eluting stents, in real-world clinical practice. [C] . Graidis C., Dimitriadis D., Ntatsios A., International Congress on Coronary Artery Disease . 2009

机译：早期和长期的临床结果从近端小伙子的近端狭窄与毒品洗脱支架，在现实世界临床实践中。
5. Analyzing the Impact of the CMS Guidance on Assuring Access to Hepatitis C Virus (HCV) Drugs on Utilization of Direct-Acting Antiviral (DAA) Agents [D] . Ferrell, Kelli Walker. 2017

机译：分析CMS指南对确保获得丙型肝炎病毒（HCV）药物对直接作用抗病毒（DAA）药物利用的影响
6. Hepatitis C Virus Variants with Decreased Sensitivity to Direct-Acting Antivirals (DAAs) Were Rarely Observed in DAA-Naive Patients prior to Treatment [O] . Doug J. Bartels, James C. Sullivan, Eileen Z. Zhang, 2013

机译：治疗前很少在未接受过DAA治疗的患者中观察到对直接作用抗病毒药（DAA）敏感性降低的丙型肝炎病毒变异株
7. 292. No association Between Direct-acting Antiviral (DAA) Therapy and Varicella-Zoster Virus (VSV) Reactivation in an Analysis of 37 Prospective Clinical Trials [O] . Maximilian Rohde, Wendy Carter 2019

机译：292.在分析37例前瞻性临床试验中，直接作用抗病毒（DAA）治疗和VariCella-Zoster病毒（VSV）重新激活之间的关联

Management of treatment with direct-acting antiviral (DAA) in clinical practice.

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