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首页> 外文期刊>Journal of paediatrics and child health >Fifteen years of acute flaccid paralysis surveillance in Hong Kong: Findings from 1997 to 2011
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Fifteen years of acute flaccid paralysis surveillance in Hong Kong: Findings from 1997 to 2011

机译：香港急性弛缓性麻痹15年监测：1997年至2011年的发现

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Aim Acute flaccid paralysis (AFP) surveillance system was set up in Hong Kong in 1997 for World Health Organization's (WHO) certification of poliomyelitis eradication. This paper describes and reviews the demographic, clinical and virological characteristics of AFP cases reported to the system in its first 15 years. Methods All patients aged under 15 years presented with acute onset of paralysis of any limbs reported to the Department of Health from January 1997 to December 2011 were reviewed. Data on demographic characteristics, vaccination history, clinical presentation and virological investigation on stool specimens collected during investigation were analysed with descriptive statistics. Results Of the 247 cases reported, about 45% were aged under five. All cases were classified as non-polio AFP according to WHO classification. About 60% were identified with neurological disorders, with Guillain-Barré syndrome (25.9%) and myelitis (13.4%) being the most common. Viruses were detected in 14.0% of the AFP cases, with non-polio enteroviruses (NPEV) (60.0%) and adenoviruses (31.4%) accounted for most of the positive detections. Most performance indicators set by the WHO were fulfilled. Conclusions The AFP surveillance facilitated the clinical, virological and epidemiological examination of paediatric AFP cases. From 1997 to 2011, Guillain-Barré syndrome and myelitis were the most common among paediatric AFP cases in Hong Kong. NPEV and adenoviruses accounted for most of the positive viral detections. No wild poliovirus was detected, and all cases were classified as non-polio AFP.
机译：目的于1997年在香港建立了急性弛缓性麻痹（AFP）监视系统，用于世界卫生组织（WHO）根除脊髓灰质炎的认证。本文描述并回顾了该系统在最初15年内向该系统报告的AFP病例的人口统计学，临床和病毒学特征。方法回顾1997年1月至2011年12月向卫生部报告的所有15岁以下四肢急性发作的患者。使用描述性统计数据分析调查期间收集的粪便标本的人口统计学特征，疫苗接种史，临床表现和病毒学调查数据。结果在报告的247例病例中，约45％年龄在5岁以下。根据WHO的分类，所有病例均被归类为非策略性AFP。大约有60％的人患有神经系统疾病，其中最常见的是格林-巴雷综合征（25.9％）和脊髓炎（13.4％）。在AFP病例中有14.0％检出病毒，其中非阳性肠病毒（NPEV）（60.0％）和腺病毒（31.4％）占了大部分阳性检出率。世卫组织设定的大多数绩效指标均已实现。结论AFP监测有助于小儿AFP病例的临床，病毒学和流行病学检查。从1997年到2011年，格林小巴综合征和脊髓炎在香港的小儿AFP病例中最常见。 NPEV和腺病毒占病毒检测的大部分阳性。未检测到野生脊髓灰质炎病毒，所有病例均归类为非脊髓灰质炎AFP。

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