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首页> 外文期刊>Journal of paediatrics and child health >Enterovirus 71 outbreak in Northern Sydney, 2013: Case series and initial response
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Enterovirus 71 outbreak in Northern Sydney, 2013: Case series and initial response

机译：2013年在悉尼北部爆发肠道病毒71型：病例系列和初步反应

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Aim Enteroviruses are a common cause of childhood disease which may manifest in a variety of ways. Enterovirus 71 (EV71) is a subtype of enterovirus which can cause meningoencephalomyelitis resulting in neurological sequelae including lethargy, weakness, ataxia, sleep myoclonus, urinary retention and, in severe cases, cardiorespiratory collapse due to neurogenic pulmonary oedema. EV71 was responsible for outbreaks in South East Asia in 1997-1998, in Western Australia in 1999 and in Sydney in 2000-2001. In 2013, we are experiencing another EV71 outbreak in Sydney. This study describes the discovery of a new outbreak in Sydney's Northern Beaches, the clinical findings as well as the public health response. Methods Thirty-seven children in total presented with presumed EV71 to the Northern Beaches Health Service from December 2012 to April 2013. Most children presented with a prodrome lasting 2-7 days prior to seeking medical attention. Sleep myoclonus was a common presenting sign occurring in 65%. Neurological signs were subtle in the majority of children and were at times missed by clinicians on a child's first presentation. Forty-six per cent of children who presented to Northern Beaches Health Service during this outbreak required a transfer to a tertiary paediatric centre for more intensive care. Results The public health investigation was important in establishing that the disease was widespread throughout the community and not as a result to exposure to a single child care setting. Identification of risk factors enabled more targeted communication to medical practitioners, child care centres and parents within the local community. Conclusions EV71 is in Australia and all clinicians seeing children in primary, secondary and tertiary care centres need to be aware of the disease, the subtle nature of initial symptoms and the potentially devastating consequences.
机译：目的肠病毒是儿童期疾病的常见原因，可能以多种方式表现出来。肠病毒71（EV71）是一种肠病毒的亚型，可引起脑膜脑脊髓炎，导致神经后遗症，包括嗜睡，虚弱，共济失调，睡眠肌阵挛，尿retention留，在严重的情况下，由于神经源性肺水肿而导致心肺功能衰竭。 EV71引起了1997-1998年东南亚，1999年西澳大利亚州和2000-2001年悉尼的暴发。 2013年，我们在悉尼再次爆发EV71。这项研究描述了在悉尼北部海滩爆发的新疾病，临床发现以及公共卫生应对措施。方法从2012年12月至2013年4月，共有37例儿童被假定患有EV71的症状。北部地区的大多数儿童在寻求医疗救助前的前庭症状持续时间为2-7天。睡眠肌阵挛是65％的常见症状。大多数儿童的神经系统症状微妙，有时在儿童首次出现时就被临床医生遗漏。在这次暴发期间向北部海滩卫生服务中心求诊的儿童中有46％需要转移到第三级儿科中心接受更深层护理。结果公共卫生调查对于确定该疾病在整个社区中广泛分布而不是不是由于接触单一儿童保育场所而造成的影响非常重要。风险因素的识别使与医生，儿童保育中心和当地社区父母之间的交流更有针对性。结论EV71在澳大利亚，所有在基层，二级和三级护理中心就诊的儿童都需要了解这种疾病，初始症状的微妙性质以及可能造成的破坏性后果。

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