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首页> 外文期刊>Journal of paediatrics and child health >The spectrum of clinical paediatric endocrinology: 28 years of referrals to an individual consultant.
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The spectrum of clinical paediatric endocrinology: 28 years of referrals to an individual consultant.

机译:临床儿科内分泌学的范围:转诊至个人顾问已有28年。

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AIM: To review referrals throughout the career of an individual paediatric endocrinologist. METHODS: A retrospective cohort study in metropolitan clinics in Queensland analysed details of all 9062 patients aged<18 years referred between January 1980 and December 2007 to determine the proportion of diagnoses in major disease categories and changes in referral patterns over time. RESULTS: Short stature (29%), type-1 diabetes mellitus (20%) and pubertal disorders (12%) accounted for most cases, with thyroid disorders (7%), obesity (6%), tall stature (5%) and hypothalamic-pituitary disorders (4%) the next commonest. An organic cause for short stature, early puberty, late puberty, tall stature and obesity was found in 39%, 32%, 19%, 15% and 6% of cases, respectively. Boys were more likely to present with short stature or delayed puberty, and girls with tall stature and early puberty. Substantially fewer boys than girls were diagnosed in infancy with congenital adrenal hyperplasia, suggesting that some may be dying undiagnosed. Comparisons between 1980 and 1984, and 2000-2004 revealed increases in the percentage of referrals for type-1 diabetes mellitus (particularly in the young), early puberty, hypothalamic-pituitary and bone disorders, and decreases in those for short and tall stature. CONCLUSIONS: Disorders of growth and puberty accounted for 52% of referrals and many have an organic cause. A neonatal screening programme for congenital adrenal hyperplasia is overdue. Changing attitudes to short and tall stature and a profound increase in new cases of diabetes mellitus indicate that substantially greater resources for treatment of childhood diabetes mellitus will be required in future.
机译:目的:回顾整个儿科内分泌科医生的职业生涯。方法:一项在昆士兰州大都会诊所进行的回顾性队列研究分析了1980年1月至2007年12月之间转诊的9062名年龄在18岁以下的所有患者的详细资料,以确定主要疾病类别的诊断比例以及转诊方式随时间的变化。结果:大多数病例为矮身材(29%),1型糖尿病(20%)和青春期疾病(12%),其中甲状腺疾病(7%),肥胖症(6%),身材高大(5%)其次是下丘脑-垂体疾病(4%)。在39%,32%,19%,15%和6%的病例中发现了身材矮小,青春期早期,青春期晚期,身材高大和肥胖的有机原因。男孩更容易出现身材矮小或青春期延迟,女孩更容易出现身材高和青春期早。被诊断为婴儿先天性肾上腺增生的男孩比女孩少得多,这表明有些人死于未确诊。 1980年与1984年以及2000-2004年之间的比较显示,1型糖尿病(尤其是年轻人),青春期早期,下丘脑-垂体和骨骼疾病的转诊百分比有所增加,而身材矮小和高大的人则有所下降。结论:生长发育和青春期疾病占转诊的52%,许多是有机原因。先天性肾上腺皮质增生的新生儿筛查程序已经过期。对身材矮小和高个子的态度的变化以及新的糖尿病病例的大量增加表明,将来将需要更多的资源来治疗儿童糖尿病。

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