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首页> 外文期刊>Journal of Oral and Maxillofacial Surgery >Island osteoperiosteal flaps with interpositional bone grafting in rabbit tibia: Preliminary study for development of new bone augmentation technique
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Island osteoperiosteal flaps with interpositional bone grafting in rabbit tibia: Preliminary study for development of new bone augmentation technique

机译:兔胫骨间骨植骨岛状骨膜瓣-新型​​骨增强技术发展的初步研究

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Purpose: Loss of alveolar vertical height is one of the most challenging conditions in the field of implantology. A few augmentation techniques have been proposed to address this challenge, including guided bone regeneration, alveolar distraction osteogenesis, sandwich osteotomies and autogenous block grafting. This is a pre-clinical study of lengthening the alveolar bone height using a thin osteoperiosteal bone flap, the "island bone flap" or i-flap, to establish vitality, stability and incorporation of the augmentation material after healing. Materials and Methods: A rabbit tibia model was designed for this study and included 8 rabbits. An osteoperiosteal osteotomy was performed through the periosteum cutting 1 mm of the outer cortex of the bone in order to elevate a bone flap. The bone flap was detached, and remained attached to the periosteum as a free floating osteoperiosteal flap, and the resultant defect was filled with xenograft. Results: The histological analysis demonstrates formation of maturing trabeculae in the site of the i-flap. In cases of trauma to the bone marrow during the surgical procedure, a centripetal gradient of bone remodeling from the surgical site toward the periphery was evident, while the bony component of the i-flap maintained vital. Conclusions: Creating a free floating osteoperiosteal flap, used here with interpositional grafting in a rabbit tibia, appears to heal by both appositional modeling and creeping substitution remodeling. Volumetric augmentation persisted despite exuberant bone turnover in this animal model. This technique holds promise as a possible augmentation bone grafting approach for use in alveolar reconstruction.
机译:目的:牙槽垂直高度的损失是植入术领域最具挑战性的条件之一。已经提出了一些增强技术来应对这一挑战,包括引导性骨再生,牙槽dis成骨,夹层截骨术和自体块移植。这是一项临床前研究,目的是使用薄的骨膜-骨膜皮瓣(“岛骨皮瓣”或i瓣)延长牙槽骨高度,以建立活力,稳定性并在愈合后掺入增强材料。材料和方法:为该研究设计了一个兔子胫骨模型,包括8只兔子。骨膜切开术是通过骨膜切开1mm的骨外皮进行的,以抬高骨瓣。分离骨瓣,并以游离的骨骨膜游离瓣附着在骨膜上,并用异种移植物填充缺损。结果:组织学分析表明在i瓣的部位形成了成熟的小梁。如果在手术过程中遭受骨髓损伤,则从手术部位向周围的骨重塑会出现向心梯度变化,而i瓣的骨性成分则至关重要。结论:创建一个自由浮动的骨膜移植瓣,在此处用于兔胫骨的间置移植,似乎可以通过并置模型和爬行替代模型修复。尽管在该动物模型中骨代谢旺盛,体积增加仍然持续。该技术有望用于牙槽重建中。

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