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首页> 外文期刊>Journal of Oral and Maxillofacial Surgery >Alveolar cleft repair in adults using guided bone regeneration with mineralized allograft for dental implant site development: a report of 2 cases.
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Alveolar cleft repair in adults using guided bone regeneration with mineralized allograft for dental implant site development: a report of 2 cases.

机译：成人用矿化同种异体骨引导植骨再生修复牙槽裂的成年牙槽裂：2例报道。

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摘要

Alveolar bone grafting is an integral part of the surgical management of oral clefts. The rationale behind alveolar cleft repair includes maxillary arch stabilization, closure of the oronasal fistula, nasal base support, nasolabial soft tissue reconstruction, and creation of bony support for tooth eruption or dental implant placement. Currently, the graft material of choice is autogenous bone graft from the anterior iliac crest. Nonetheless, autogenous bone grafting carries the significant risk of donor-site morbidity, leads to postoperative pain, and entails an additional operative cost. With the success of allograft bone material in implant site development, we explore the option of using human mineralized cancellous bone allograft in alveolar cleft patients. This article reports on the success of using mineralized human allograft to treat 2 adult patients with severe alveolar cleft defects. The repairs were accomplished with a guided bone regeneration technique without the use of any autogenous bone, with subsequent successful placement of endosseous implants. This opens up the possibility of avoiding harvesting iliac crest bone graft and its associated morbidities and expense by use of only mineralized allograft and a guided bone regeneration technique in an outpatient office setting.
机译：牙槽骨移植是口腔裂隙外科治疗不可或缺的一部分。牙槽裂修复的基本原理包括上颌弓稳定，口鼻瘘闭合，鼻基支撑，鼻唇软组织重建以及为牙齿萌出或植入牙种植体创建骨支撑。当前，选择的移植物材料是来自前terior的自体骨移植物。然而，自体骨移植具有供体部位发病的显着风险，导致术后疼痛，并需要额外的手术费用。随着同种异体骨材料在种植体部位发展中的成功应用，我们探索了在牙槽裂患者中使用人矿化的松质骨同种异体移植的选择。本文报道了使用矿化的人类同种异体移植治疗2例严重肺泡裂缺损的成年患者的成功经验。修复是通过引导性骨再生技术完成的，无需使用任何自体骨，随后成功放置了骨内植入物。这为在门诊就诊时仅使用矿化的同种异体移植物和引导性骨再生技术提供了避免收获骨移植物及其相关发病率和费用的可能性。

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