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首页> 外文期刊>Clinics in dermatology >Autografts and cultured epidermis in the treatment of vitiligo.
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Autografts and cultured epidermis in the treatment of vitiligo.

机译：自体移植和表皮培养治疗白癜风。

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摘要

Skin transplants can be a useful and efficacious method to treat vitiligo. The aim is to repopulate areas lacking melanocytes with functional cells taken from normally pigmented areas. Several procedures have been devised and tested: some consist in the simple transfer of epidermis sampled and implanted as is, whereas others are based on the transplantation of disaggregated and manipulated cells. The therapeutic success of the former methods is partly determined by the ability and experience of the surgeon performing the operation, whereas the results of the latter methods mainly depend on the laboratory facilities and abilities of the personnel who manipulate the cells to be transplanted. The transplantation of cultured cells is the most fascinating and promising procedure but requires the observance of still not completely predictable procedures. The use of biological material of animal origin and the use of factors to stimulate cell proliferation, such as growth factors and promoting agents, are other points that require attention.
机译：皮肤移植可能是治疗白癜风的一种有用且有效的方法。目的是用取自正常色素区域的功能性细胞重新填充缺乏黑素细胞的区域。已经设计和测试了几种方法：一些方法包括按原样取样和植入表皮的简单转移，而另一些方法则基于分解和操纵的细胞的移植。前一种方法的治疗成功部分取决于外科医生进行手术的能力和经验，而后一种方法的结果主要取决于实验室设施和操纵要移植细胞的人员的能力。培养细胞的移植是最令人着迷和最有前途的过程，但是需要遵守尚不完全可预测的过程。其他需要注意的问题是使用动物来源的生物材料以及使用刺激细胞增殖的因子，例如生长因子和促进剂。

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