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首页> 外文期刊>Journal of neurology >Patients with psychogenic nonepileptic seizures, alone or epilepsy-associated, share a psychological profile distinct from that of epilepsy patients.
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Patients with psychogenic nonepileptic seizures, alone or epilepsy-associated, share a psychological profile distinct from that of epilepsy patients.

机译:患有单独或与癫痫相关的精神病性非癫痫性发作的患者具有与癫痫患者不同的心理特征。

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摘要

The aim of this study was twofold: 1 - to identify a psychological profile of patients with psychogenic nonepileptic seizures (PNESs) that is possibly distinct from that of subjects affected by epileptic seizures (ESs) alone; 2 - to detect the possible differences between the clinical features and psychological profile of patients affected by PNESs alone and those of subjects in whom PNESs are associated with epileptic seizures (ES/PNES patients).We assessed the psychological profiles of 2 different groups of subjects. The first group was of 38 patients who had all developed PNESs after epileptic seizures (ESPNES, group 1). The second group was of 31 patients with PNESs alone (PNES, group 2). We compared the psychological findings of each of these 2 groups with those of 2 control groups, composed of patients who matched groups 1 and 2 for sex, age, and educational level, but who were affected only by ESs (groups 1C and 2C). Finally, we considered possible differences between the ictal symptoms and signs of PNESs occurring in ES/PNES and in PNES patients.Both the ES/PNES group and the PNES group revealed higher percentages of Somatoform Disorders and Cluster B Personality Disorders (DSM-III-R diagnoses) than the ES patients in the control groups. The scores obtained on the Psychophysiological Distress Scale of the Cognitive Behavioural Assessment Battery (CBA) followed the same pattern.Among PNES ictal phenomena, autonomic symptoms and signs were significantly more frequent in the PNES than in the ES/PNES group. The occurrence of PNESs mimicking generalised tonic-clonic ESs (GTC-PNESs) was significantly associated with a low academic level.The results of this study suggest that the patients with PNESs alone and those affected by PNESs and ESs share the same psychological profile, which is different from that of patients with ESs alone. However, some differences between ES/PNES and PNES patients were found in the clinical semiology of their PNESs. Our findings could have implications for the diagnosis and for the treatment of patients with PNESs.
机译:这项研究的目的是双重的:1-确定精神病性非癫痫性癫痫发作(PNESs)患者的心理状况,这可能与仅受癫痫性癫痫发作(ESs)影响的受试者的心理状况不同; 2-检测仅受PNESs影响的患者和与PNESs伴有癫痫发作的受试者(ES / PNES患者)的临床特征和心理特征之间的可能差异。我们评估了两组不同受试者的心理特征。第一组是38例在癫痫发作后全部发展为PNES的患者(ES PNES,第1组)。第二组是31例单独的PNESs患者(PNES,第2组)。我们将这两组的心理结果与两组的心理结果进行了比较,这两组患者的性别,年龄和教育水平均与第1组和第2组匹配,但仅受ES影响(第1C和2C组)。最后,我们考虑了ES / PNES和PNES患者的PNESs发作的症状和体征的可能差异。ES/ PNES组和PNES组均显示较高的躯体形式障碍和B组人格障碍(DSM-III- (R诊断)高于对照组的ES患者。在认知行为评估电池组(CBA)的心理生理困扰量表上获得的分数遵循相同的模式。在PNES的发作现象,自主神经症状和体征中,PNES的发生频率明显高于ES / PNES组。模仿一般性强直阵挛性ESs(GTC-PNESs)的PNESs的发生与低学历水平显着相关。本研究的结果表明,仅PNESs的患者以及受PNESs和ESs影响的患者具有相同的心理特征,与仅ES患者不同。但是,ES / PNES和PNES患者之间在其PNES的临床符号学上存在一些差异。我们的发现可能对PNESs患者的诊断和治疗产生影响。

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