Botulinum toxin in patients with multiple sclerosis.

Kabus C; Hecht M; Japp G; Jost WH; Pohlau D; Stuckrad Barre S; Winterholler M

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Botulinum toxin in patients with multiple sclerosis.

机译：多发性硬化症患者的肉毒杆菌毒素。

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Nearly all patients with multiple sclerosis (MS) will develop spasticity in the course of their disease. This symptom accounts for most of the handicap and impairment in the quality of life. Treatment with botulinum toxin will enable an efficient and safe alleviation of spasticity and the problems involved, given a realistic definition of the therapeutic target and a graded multimodal approach. Treatment may fail for a great number of reasons that require diligent analysis. Compared with other disorders resulting in spasticity as well, MS does not constitute a monophasic disorder but is influenced by many factors. Treatment of spasticity in MS must therefore be guided by its particular aspects.

机译：几乎所有多发性硬化症（MS）患者在病程中都会出现痉挛。这种症状是造成生活质量障碍的主要原因。给定治疗目标的实际定义和分级多模式方法，用肉毒杆菌毒素进行的治疗将能够有效安全地缓解痉挛和所涉及的问题。治疗可能由于许多原因而失败，需要进行认真的分析。与也导致痉挛的其他疾病相比，MS并非单相疾病，而是受许多因素影响。因此，MS痉挛的治疗必须以其特定方面为指导。

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来源
《Journal of neurology》 |2006年第1期|共3页
作者
Kabus C; Hecht M; Japp G; Jost WH; Pohlau D; Stuckrad Barre S; Winterholler M;
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正文语种 eng
中图分类神经病学与精神病学;
关键词
Botulinum Toxin Type A; Multiple Sclerosis; Neuromuscular Agents; 肉毒杆菌毒素; A型; 多发性硬化; 神经肌肉药;

机译：Botulinum Toxin Type A;Multiple Sclerosis;Neuromuscular Agents;肉毒杆菌毒素;A型;多发性硬化;神经肌肉药;

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1. Early physiotherapy after injection of botulinum toxin increases the beneficial effects on spasticity in patients with multiple sclerosis. [J] . Giovannelli M, Borriello G, Castri P, Clinical rehabilitation . 2007,第4期

机译：注射肉毒杆菌毒素后的早期物理疗法可增加多发性硬化症患者痉挛的有益作用。
2. Botulinum toxin improves dysphagia associated with multiple sclerosis. [J] . Restivo DA, Marchese Ragona R, Patti F, European journal of neurology: the official journal of the European Federation of Neurological Societies . 2011,第3期

机译：肉毒杆菌毒素可改善与多发性硬化症相关的吞咽困难。
3. The place of the botulinum toxin in the management of multiple sclerosis. [J] . Habek M, Karni A, Balash Y, Clinical neurology and neurosurgery . 2010,第7期

机译：肉毒杆菌毒素在多发性硬化症管理中的地位。
4. Clinical Use of Botulinum Toxin in Spasticity Case Description: Severe Adverse Effect with the Use of the Chinese Botulinum Toxin - Prosigne~R [C] . M. Sposito International Society of Physical and Rehabilitation Medicine . 2007

机译：骨髓蛋白在痉挛性案例中的临床应用案例描述：对使用中国肉毒杆菌毒素的严重不良影响 - ProSigne〜R
5. A biophysical characterization of botulinum toxin and cholera toxin. [D] . Kuziemko, Geoffrey Matthew. 1997

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6. Protocol for a prospective observational study of cortical lower urinary tract control changes following intradetrusor injection of botulinum toxin-A in patients with multiple sclerosis [O] . Rodolfo A Elizondo, Christof Karmonik, Timothy B Boone, 2017

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7. Clinical effectiveness of intradetrusor injections of botulinum toxin type a in dose 100 units in multiple sclerosis patients with neurogenic detrusor overactivity [O] . Еkaterina S. Filippova, Igor V. Bazhenov, Aleksandr V. Zyrjanov, 2020

机译：肉毒杆菌毒素型肉毒杆菌毒素型患者患者的临床疗效100单位在多发性裂解器过度患者中的多发性肺炎患者中

Botulinum toxin in patients with multiple sclerosis.

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