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首页> 外文期刊>Journal of neurology >Cerebral infarction in bacterial meningitis: predictive factors and outcome.
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Cerebral infarction in bacterial meningitis: predictive factors and outcome.

机译:细菌性脑膜炎的脑梗塞:预测因素和预后。

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摘要

In this study, we analysed the frequency, morphological patterns and clinical characteristics of cerebral ischaemia in bacterial meningitis. We sought to determine predictors for the development of vasculopathy and ischaemic infarction in patients with bacterial meningitis. Consecutive adult patients admitted between March 1998 and February 2009 to a neurological intensive care unit at a university hospital in Germany with the diagnosis of bacterial meningitis were included in the study. Standard criteria were used to define bacterial meningitis. From 68 patients with bacterial meningitis, six patients suffered from cerebral ischaemia (8.8%). In our cohort, reduced level of consciousness on admission (p = 0.01) and lower white blood cell (WBC) count in cerebrospinal fluid (CSF) (p = 0.012) were associated with development of ischaemic cerebrovascular complications. The short-term outcome of all patients was poor (median modified Rankin scale 4.5). In patients presenting with reduced level of consciousness on admission and/or low WBC count in CSF early cerebral imaging including MR angiography or CT angiography are warranted to detect impending cerebrovascular complications.
机译:在这项研究中,我们分析了细菌性脑膜炎脑缺血的频率,形态学模式和临床特征。我们试图确定细菌性脑膜炎患者血管病变和缺血性梗死发展的预测因素。该研究包括1998年3月至2009年2月在德国某大学医院的神经内科重症监护病房接受诊断为细菌性脑膜炎的连续成年患者。使用标准标准来定义细菌性脑膜炎。在68例细菌性脑膜炎患者中,有6例患有脑缺血(8.8%)。在我们的队列中,入院时意识水平降低(p = 0.01)和脑脊液(CSF)白细胞计数降低(p = 0.012)与缺血性脑血管并发症的发生有关。所有患者的短期预后均较差(中位改良兰金评分表4.5)。对于入院意识水平降低和/或CSF中WBC计数低的患者,应早期进行包括MR血管造影或CT血管造影在内的脑部影像学检查,以发现即将发生的脑血管并发症。

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