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首页> 外文期刊>Journal of neurology >Oral pulsed high-dose dexamethasone for myositis.
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Oral pulsed high-dose dexamethasone for myositis.

机译:口服脉冲大剂量地塞米松治疗肌炎。

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摘要

To study the short-term effect of oral pulsed high-dose dexamethasone for myositis we treated eight newly diagnosed patients with three 28-day cycles of oral dexamethasone. Primary outcome measures were muscle strength, pain, and serum creatine kinase activity. Six patients responded. Side effects were mild. At follow-up five responders were still in remission, without medication. Pulsed high-dose dexamethasone seems beneficial in myositis. A larger, prednisone-controlled trial is justified to analyze long-term efficacy.
机译:为了研究口服脉冲大剂量地塞米松治疗肌炎的近期效果,我们对三个新诊断的患者进行了三个28天口服地塞米松周期治疗。主要结局指标为肌肉力量,疼痛和血清肌酸激酶活性。六例患者有反应。副作用轻微。随访时,五名缓解者仍未使用药物而缓解。脉冲大剂量地塞米松似乎对肌炎有益。较大的泼尼松对照试验有理由分析长期疗效。

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