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首页> 外文期刊>Journal of neurology >Upbeat nystagmus as a clinical sign of physostigmine-induced right occipital non-convulsive status epilepticus.
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Upbeat nystagmus as a clinical sign of physostigmine-induced right occipital non-convulsive status epilepticus.

机译：乐观的眼球震颤是毒扁豆碱诱导的右枕非惊厥性癫痫持续状态的临床体征。

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Dear Sirs,The main indication for use of physostigmine is treatment of anticholinergic coma after anaesthesia and intoxication. Generalized epileptic seizures are known complications of physostigmine, whereas focal seizures and non-convulsive status epilepticus (NCSE) have not been described as complications in this setting [1]. Epileptic nystagmus (EN) is a rare clinical sign of seizures defined as repetitive jerking of the eyes secondary to epileptic activity. EN usually occurs as horizontal nystagmus with its fast phase beating away from the epileptogenic hemisphere [2]. Purely vertical beating EN on the contrary is unusual and has been described only a few times in the setting of bilateral epileptic activity [3]. We present a patient in whom cholinergic treatment with physostigmine resulted in right occipital NCSE presenting with upbeat nystagmus and prolonged impairment of consciousness documented on video electroencephalogram (EEG).
机译：亲爱的先生们，使用毒扁豆碱的主要适应症是麻醉和中毒后抗胆碱能昏迷的治疗。全身性癫痫发作是毒扁豆碱的已知并发症，而局灶性癫痫和非惊厥性癫痫持续发作（NCSE）在这种情况下并未被描述为并发症[1]。癫痫性眼球震颤（EN）是一种罕见的癫痫发作临床症状，其定义为继发于癫痫活动的眼睛反复抽搐。 EN通常以水平眼球震颤的形式出现，其快相远离癫痫发作半球[2]。相反，纯垂直跳动EN是不常见的，在双侧癫痫发作活动中仅描述过几次[3]。我们介绍了一个患者，使用毒扁豆碱进行胆碱能治疗会导致右枕NCSE呈现出乐观的眼球震颤和长时间的意识障碍，这在视频脑电图（EEG）中有记载。

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