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首页> 外文期刊>Journal of neurology >Aseptic meningo-radiculo-encephalitis presenting initially with urinary retention : A variant of acute disseminated encephalomyelitis.
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Aseptic meningo-radiculo-encephalitis presenting initially with urinary retention : A variant of acute disseminated encephalomyelitis.

机译:无菌性脑膜神经根性脑炎最初表现为尿radi留:急性弥漫性脑脊髓炎的一种变体。

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摘要

We report three male patients with aseptic meningoencephalo- radiculitis presenting with acute urinary retention.Viral antibody titers for herpes types I and II and the PCR studies were negative. The cerebrospinal fluid revealed elevated myelin basic protein.The serum antibodies against a panel of gangliosides, some of which are known to be associated with acquired demyelinating neuropathies, were all negative.The magnetic resonance imaging (MRI) studies revealed spotty T2 high intensities in the basal ganglia, thalamus and brainstem in two patients. In one patient,meningeal gadolinium enhancement of the conus and cauda equina of the spinal cord was recognized. On urodynamic studies, all patients showed features of atonic bladder with or without detrusor hyperactivity. They were treated conservatively without using steroids or immunoglobulins, and made a remarkable functional recovery with the disappearance of abnormal MRI findings.However, all three were left with erectile dysfunction, and two continued to use self-intermittent catheterization at more than 3-year follow-up.There was no recurrence of symptoms. The underlying causes remain unclear, though they may represent a variant of acute disseminated encephalomyelitis.
机译:我们报告了三名男性无菌性脑膜脑神经根神经炎患者,并伴有急性尿retention留。I型和II型疱疹病毒抗体滴度和PCR研究均为阴性。脑脊液显示髓鞘碱性蛋白升高,针对一组神经节苷脂的血清抗体均为阴性,其中一些与已知的获得性脱髓鞘性神经病有关,而磁共振成像(MRI)研究显示该组织中斑点T2高强度。基底节,丘脑和脑干2例。在一名患者中,发现脊髓的圆锥形和马尾状脑膜g增强。在尿流动力学研究中,所有患者均表现为伴或不伴逼尿肌亢进的无力性膀胱功能。他们在不使用类固醇或免疫球蛋白的情况下进行了保守治疗,并且随着MRI异常消失而获得了显着的功能恢复。然而,三名患者均存在勃起功能障碍,其中两名在随访3年后继续使用自间歇性导尿-向上。没有症状复发。尽管它们可能代表急性播散性脑脊髓炎的一种变体,但其根本原因仍不清楚。

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