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首页> 外文期刊>Journal of neurology >Nociceptive pathway function is normal in cervical dystonia: A study using laser-evoked potentials
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Nociceptive pathway function is normal in cervical dystonia: A study using laser-evoked potentials

机译：颈肌张力障碍的伤害感受途径功能正常：一项利用激光诱发电位的研究

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摘要

Cervical dystonia (CD) is often associated with pain in the neck muscles, though the mechanisms underlying pain in this condition are still largely unknown. The aim of this study was to assess laser pain rating and CO 2 laserevoked potentials (LEPs) in CD patients with pain in the posterior neck region. We assessed the N2/P2 LEP complex and laser pain rating in a group of 20 CD patients and in 21 normal subjects. In 11 of the 20CDpatients (group I), the N2/ P2 complex was recorded after stimulation of the skin overlying the right and left deltoid muscles (painless and non-dystonic). In the remaining nine CD patients (group II), the N2/P2 complex was recorded after stimulation of the skin over the splenius capitis muscle (painful and dystonic) and after stimulation of the skin overlying the contralateral splenius muscle (painless and non-dystonic). In group I patients, the N2/P2 LEP amplitude and laser pain rating after stimulation of both shoulders did not differ significantly from those obtained in normal subjects. Similarly, in group II patients, the N2/P2 LEP amplitude and laser pain rating after stimulation of the painful and dystonic splenius capitis muscle did not differ significantly from those obtained from either the contralateral painless, non-dystonic splenius capitis or normal subjects. The results of this study demonstrate that cutaneous nociceptive pathway function in CD patients is normal, thereby indicating that muscle pain in CD is not associated with any central sensitization of nociceptive inputs in either painful (dystonic) or non-painful (non-dystonic) body areas.
机译：颈肌张力障碍（CD）通常与颈部肌肉疼痛有关，尽管在这种情况下引起疼痛的机制仍然未知。这项研究的目的是评估颈部后部疼痛的CD患者的激光疼痛等级和CO 2激光诱发电位（LEP）。我们评估了一组20名CD患者和21名正常受试者的N2 / P2 LEP复合物和激光疼痛等级。在20名CDCD患者中，有11名患者（第一组）在刺激左右三角肌（无痛和非肌张力障碍）上皮后记录了N2 / P2复合物。在其余9名CD患者（II组）中，在脾脏脾炎肌上刺激皮肤（疼痛和肌张力障碍）和对侧脾脏肌之上覆盖皮肤（无痛和非肌张力障碍）后记录了N2 / P2复合物）。在第一组患者中，双肩刺激后的N2 / P2 LEP振幅和激光疼痛等级与正常受试者的无明显差异。同样，在第二组患者中，刺激疼痛性和肌张力障碍性脾脏Capitis肌肉后的N2 / P2 LEP幅度和激光疼痛评级与对侧无痛性，非肌张力障碍性脾脏炎或正常受试者的无明显差异。这项研究的结果表明，CD患者的皮肤伤害感受途径功能正常，从而表明CD的肌肉疼痛与疼痛（张力性）或非疼痛（非张力性）身体的伤害性输入的任何中枢敏化无关地区。

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