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Rheumatoid arthritis, new standards of care: nursing implications of infliximab

机译:类风湿关节炎,新的治疗标准:英夫利昔单抗的护理意义

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摘要

The apparent central role of tumour necrosis factor alpha (TNFalpha) in the pathophysiology of rheumatoid arthritis suggests that anti-TNFalpha therapy may provide prolonged therapeutic benefits. This article describes the use of Infliximab (REMI-CADE?, Centocor, Inc. Malvern, PA), a chimeric monoclonal antibody that binds with high affinity and specificity to TNFalpha. Patient management and education, infusion preparation, dosing and administration, and patient monitoring are all explored in relation to nursing care. Finally, the health care professional's perspective is given.
机译:肿瘤坏死因子α(TNFalpha)在类风湿关节炎的病理生理中的明显中心作用表明,抗TNFα治疗可能会提供长期的治疗益处。本文介绍了英夫利昔单抗(REMI-CADE?,Centocor,Inc. Malvern,PA)的使用,它是一种与TNFα高亲和力和特异性结合的嵌合单克隆抗体。与护理有关,探讨了患者管理和教育,输液准备,给药和给药以及患者监测。最后,给出了医疗保健专业人员的观点。

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