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METHOD FOR DECIDING EFFICACY OF INFLIXIMAB MEDICINAL EFFECT IN PATIENT WITH RHEUMATOID ARTHRITIS

机译:一种确定类风湿关节炎患者抗炎药疗效的方法

摘要

PROBLEM TO BE SOLVED: To provide a method for efficiently and effectively discriminating the presence or absence of the efficacy of an infliximab administering on a gene level by analyzing the gene expression profile of a blood sample.;SOLUTION: The method for discriminating the efficacy of the infliximab medicinal effect in a patient with rheumatoid arthritis using one or more indicators selected from a plurality of indicators includes: a process for measuring the expression level of one or more genes selected from a specific group in blood of the patient with rheumatoid arthritis; a process for analyzing the measured expression level, using the gene expression profile prepared beforehand; and a process for discriminating the efficacy of infliximab medicinal effect in the patient with rheumatoid arthritis based on the analysis result.;COPYRIGHT: (C)2011,JPO&INPIT
机译:解决的问题:提供一种通过分析血液样品的基因表达谱,在基因水平上有效,有效地区分英夫利昔单抗给药的有效性的方法;解决方案:使用选自多种指示剂的一种或多种指示剂在类风湿关节炎患者中的英夫利昔单抗的药物作用包括:测量选自类风湿性关节炎患者血液中的一种或多种基因的表达水平的方法;使用预先准备的基因表达谱分析测定的表达水平的方法;分析结果的基础上,确定英夫利昔单抗在类风湿关节炎患者中的疗效。[COPYRIGHT:(C)2011,JPO&INPIT

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