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首页> 外文期刊>Journal of orthopaedic research >Long-term hip simulator testing of the artificial hip joint bearing surface grafted with biocompatible phospholipid polymer
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Long-term hip simulator testing of the artificial hip joint bearing surface grafted with biocompatible phospholipid polymer

机译:生物相容性磷脂聚合物接枝的人工髋关节轴承表面的长期髋关节模拟器测试

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摘要

To prevent periprosthetic osteolysis and subsequent aseptic loosening of artificial hip joints, we recently developed a novel acetabular highly cross-linked polyethylene (CLPE) liner with graft polymerization of 2-methacryloyloxyethyl phosphorylcholine (MPC) on its surface. We investigated the wear resistance of the poly(MPC) (PMPC)-grafted CLPE liner during 20 million cycles in a hip joint simulator. We extended the simulator test of one liner to 70 million cycles to investigate the long-term durability of the grafting. Gravimetric, surface, and wear particle analyses revealed that PMPC grafting onto the CLPE liner surface markedly decreased the production of wear particles and showed that the effect of PMPC grafting was maintained through 70 million cycles. We believe that PMPC grafting can significantly improve the wear resistance of artificial hip joints.
机译:为了防止假体周围的骨溶解和随后的人工髋关节无菌性松动,我们最近开发了一种新型髋臼高交联聚乙烯(CLPE)衬里,其表面接枝了2-甲基丙烯酰氧基乙基磷酰胆碱(MPC)的聚合反应。我们在髋关节模拟器中研究了2000万个周期的聚(MPC)(PMPC)接枝CLPE衬里的耐磨性。我们将一个衬管的仿真器测试扩展到7,000万次循环,以研究接枝的长期耐久性。重量分析,表面分析和磨损颗粒分析表明,PMPC接枝到CLPE衬里表面上明显减少了磨损颗粒的产生,并表明PMPC接枝的效果可以保持7千万次循环。我们认为,PMPC接枝可以显着改善人工髋关节的耐磨性。

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