...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of orthopaedic research >Improved anchorage in osteoporotic vertebrae with new implant designs.
【24h】

Improved anchorage in osteoporotic vertebrae with new implant designs.

机译：采用新的植入物设计，改善了骨质疏松椎骨的固定。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The goal of our study was to evaluate two newly developed implant designs and their behavior in terms of subsidence in lumbar vertebral bodies under cyclic loading. The new implants were evaluated in two different configurations (two small prototypes vs. one large prototype with similar load-bearing area) in comparison to a conventional screw-based implant (MACS TL). A pool of 13 spines with a total of 65 vertebrae was used to establish five testing groups of similar bone mineral density (BMD) distribution with eight lumbar vertebrae each. In additional to BMD assessment via dual-energy X-ray absorptiometry, cancellous BMD and structural parameters were determined using a new generation in vivo 3D-pQCT. The specimens were loaded sinusoidally in force control at 1 Hz for 1000 cycles at three load levels (100, 200, and 400 N). A survival analysis using the number of cycles until failure (Cox regression with covariates) was applied to reveal differences between implant groups. All new prototype configurations except the large cylinder survived significantly longer than the control group. The number of cycles until failure was significantly correlated with the structural parameter Tb.Sp. and similarly with the cancellous BMD for three of five implants. In both large prototypes the cycle number until failure significantly correlated with the preoperative distance to the upper endplates. Although the direct relationship between bone structure or density and mechanical breakage behavior cannot be conclusively proven, all the prototypes adapted for poor bone structure performed better than the comparable conventional implant.
机译：我们的研究目的是评估两种新开发的植入物设计及其在周期性载荷下腰椎椎体下陷的行为。与传统的基于螺钉的植入物（MACS TL）相比，以两种不同的配置对新的植入物进行了评估（两个小原型与一个具有相似承重面积的大型原型）。使用13个脊椎池（总共65个椎骨）来建立五个相似骨矿物质密度（BMD）分布的测试组，每个组具有8个腰椎。除了通过双能X射线吸收法进行BMD评估外，还使用新一代的体内3D-pQCT确定了松质BMD和结构参数。在三个载荷水平（100、200和400 N）下，以1 Hz的力控制以正弦形式将试样进行1000次循环正弦加载。应用直到失败的周期数的生存分析（具有协变量的Cox回归），以揭示植入物组之间的差异。除大型气缸外，所有其他新原型配置的存活时间均比对照组长。直到失效的周期数与结构参数Tb.Sp显着相关。对于五分之三的植入物，也采用松质骨密度。在这两个大型原型中，直到失效的周期数与距上端板的术前距离显着相关。尽管无法最终证明骨骼结构或密度与机械断裂行为之间的直接关系，但所有适用于不良骨骼结构的原型都比同类传统植入物表现更好。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号