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首页> 外文期刊>Journal of orthopaedic research >Biceps tendon properties worsen initially but improve over time following rotator cuff tears in a rat model.
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Biceps tendon properties worsen initially but improve over time following rotator cuff tears in a rat model.

机译：在大鼠模型中，二头肌的肌腱特性最初会恶化，但随着肩袖撕裂而随着时间的推移会改善。

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Damage to the biceps tendon is often seen in conjunction with rotator cuff tears. However, controversy exists regarding its role in the shoulder and its optimal treatment. A previous study determined that biceps tendons were detrimentally affected in the presence of rotator cuff tears in the rat model and this damage worsened over time. However, whether this damage progresses at later time points to provide a chronic model is unknown. The objective of this study was to determine the changes in the biceps tendon in the presence of a cuff tear over time. Our hypothesis was that histological, compositional, organizational, and mechanical properties would worsen with time. We detached the supraspinatus and infraspinatus tendons of 48 rats and evaluated these properties at 1, 4, 8, and 16 weeks postdetachment. Properties worsened through 8 weeks, but improved between 8 and 16 weeks. We therefore conclude that biceps tendon changes in this model are not truly chronic. Additionally, it has been shown that infraspinatus properties in this model return to normal by 16 weeks, when biceps properties improve, indicating that earlier repair of one or more of the rotator cuff tendons may lead to resolved pathology of the long head of the biceps tendon.
机译：肱二头肌腱损伤常与肩袖撕裂结合在一起。但是，关于其在肩部的作用及其最佳治疗方法存在争议。先前的一项研究表明，在大鼠模型中，肩袖撕裂的存在对二头肌肌腱造成了不利影响，并且随着时间的流逝，这种损害进一步加剧。但是，这种损伤是否在以后的时间点发展以提供慢性模型尚不清楚。这项研究的目的是确定存在袖带撕裂的情况下肱二头肌腱的变化。我们的假设是组织学，成分，组织和机械特性会随着时间而恶化。我们分离了48只大鼠的棘上肌和棘下肌肌腱，并在分离后1、4、8和16周评估了这些特性。性能在8周内恶化，但在8周和16周之间有所改善。因此，我们得出的结论是，该模型中的二头肌肌腱变化并不是真正的慢性。另外，已经表明，当二头肌特性改善时，该模型的鼻下肌特性在16周后恢复正常，这表明较早修复一个或多个肩袖肌腱可能导致二头肌肌腱长头的病变得以解决。 。

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