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首页> 外文期刊>Clinics in dermatology >Flavonoids as components of biologically active cosmeceuticals.
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Flavonoids as components of biologically active cosmeceuticals.

机译:类黄酮作为生物活性药妆的成分。

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摘要

Flavonoids are multi-active components used in common cosmetics primarily for antioxidant and soothing actions. Despite this, their multi-active properties are far from being fully used. It is well known that many flavonoids provide protection from telangiectasias and petechias caused by ruptured blood vessels. Thus, the notion of a "strengthening" effect of these compounds on blood vessel walls is common. The activity of flavonoids on skin blood vessels is complex. Three main components of their activity can be distinguished: blood vessel protection, platelet aggregation prevention, and capillary permeability decrease. Each of these components is realized with the participation of several mechanisms differing on the types of receptors that the flavonoids affect. Some of them consist of a direct action on the enzymes responsible for the synthesis of substances of tissue hormone character, such as thromboxanes, histamine, or platelet activating factor. The mechanisms based on less or more indirect activity can also be met. At least 11 points for activity can be distinguished among flavonoids' actions on blood vessels.
机译:类黄酮是常见化妆品中使用的多种活性成分,主要用于抗氧化剂和舒缓作用。尽管如此,它们的多活性特性仍未得到充分利用。众所周知,许多黄酮类化合物可防止血管破裂引起的毛细血管扩张和瘀斑。因此,这些化合物对血管壁的“增强”作用的观念是普遍的。类黄酮在皮肤血管上的活性很复杂。可以区分其活动的三个主要组成部分:血管保护,防止血小板聚集和毛细血管通透性降低。这些成分中的每一个都是在黄酮类化合物影响的受体类型不同的几种机制的参与下实现的。它们中的一些直接作用于负责组织激素特性物质合成的酶,例如血栓烷,组胺或血小板活化因子。也可以满足基于更少或更多间接活动的机制。在类黄酮对血管的作用中,至少可以区分11点活性。

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