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首页> 外文期刊>Journal of oral rehabilitation >An in vitro investigation of the effect of some analgesics on human enamel.
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An in vitro investigation of the effect of some analgesics on human enamel.

机译：某些止痛药对人牙釉质影响的体外研究。

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The sale of over-the-counter pain relief medication has increased dramatically in recent years, and typically amounts to several hundred thousands of pounds per year in the UK. Many soluble analgesic preparations contain citric acid, and it has been suggested that these formulations may cause dental erosion. The aim of this study was to investigate the effect of some over-the-counter analgesics on tooth surface loss from human enamel. Six commonly available analgesics were chosen for this study and the effect of immersing unerupted human enamel was examined using non-contact optical profilometry. Two of the six analgesics investigated caused no detectable erosion (Boots soluble aspirin and Anadin Extra(TM)). Three caused statistically significant enamel erosion, but this was very slight and is thought to be clinically insignificant (Alka Seltzer(TM), Panadol(TM) and Solpadeine(TM)). Only one analgesic caused possible potentially clinical significant enamel erosion. Further studies are needed to determine whether Aspro(TM) causes clinically significant enamel erosion.
机译：近年来，非处方止痛药的销售量急剧增加，在英国通常每年达到数十万英镑。许多可溶性镇痛剂都含有柠檬酸，并且有人建议这些制剂可能引起牙齿腐蚀。这项研究的目的是研究一些非处方镇痛药对人牙釉质牙齿表面脱落的影响。本研究选择了六种常用的止痛药，并使用非接触式光学轮廓测定法检查了未喷出的人类牙釉质的浸入效果。所研究的六种镇痛药中有两种没有引起可检测的侵蚀（Boots可溶性阿司匹林和Anadin Extra™）。三者引起了统计上显着的牙釉质侵蚀，但是这是非常轻微的，并且据认为在临床上是微不足道的（Alka Seltzer TM，Panadol TM和Solpadeine TM）。只有一种止痛药可能引起潜在的临床上明显的牙釉质糜烂。需要进一步的研究以确定Aspro™是否引起临床上明显的牙釉质侵蚀。

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