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首页> 外文期刊>Journal of pediatric hematology/oncology: Official journal of the American Society of Pediatric Hematology/Oncology >Middle Cerebral Artery Stroke in a Neonate With a Congenital Hypercoagulable Condition Following Repair of an H-type Tracheoesophageal Fistula
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Middle Cerebral Artery Stroke in a Neonate With a Congenital Hypercoagulable Condition Following Repair of an H-type Tracheoesophageal Fistula

机译：H型气管食管瘘修复后的先天性高凝状态新生儿中脑中风。

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摘要

We report a case of middle cerebral artery stroke with heterozygosity for 2 separate hypercoagulable conditions following repair of an H-type tracheoesophageal fistula (TEF) in an infant. Neonatal stroke is rare, occurring in 1 in 4000 births annually in the United States. Stroke after pediatric surgery occurs in approximately 0.05% of patients. Etiologies of stroke in neonates include cardiac, hematologic, vascular, traumatic, metabolic, pharmacologic, infectious, and hypoxemic insults. Thrombophilia has been described in 42% to 78% of neonates with neonatal stroke. Stroke after repair of an H-type TEF has not been reported as a postoperative complication. Manipulation of the carotid artery during this operation is presumed to have contributed to a thromboembolic event in this infant with a hypercoagulable state. Whereas preoperative workup may not be indicated due to the low prevalence of neonatal stroke, workup for a congenital hypercoaguable condition may be considered in infants with stroke as a postoperative complication. This report provides a concise review of the etiology and treatment of stroke and hypercoagulable states in neonates as well as presents the case of a previously undescribed complication of repair of an H-type TEF.
机译：我们报告了一个婴儿H型气管食管瘘（TEF）修复后杂合性为2个单独的高凝条件的大脑中动脉卒中的情况。新生儿中风很少见，在美国每年发生的婴儿中有4000例中有1例发生。小儿手术后的中风发生率约为0.05％。新生儿中风的病因包括心脏，血液，血管，创伤，代谢，药理，感染和低氧血症。已有42％至78％的新生儿卒中新生儿描述有血栓形成倾向。尚未报道H型TEF修复后的中风为术后并发症。据推测，在该手术过程中，该颈动脉的操作已导致该高凝状态婴儿的血栓栓塞事件。由于新生儿卒中的患病率较低，因此可能不建议进行术前检查，而对于患有脑卒中的婴儿，可以考虑对先天性高凝状态进行检查。该报告简要概述了新生儿中风和高凝状态的病因和治疗，并介绍了以前未描述的H型TEF修复并发症。

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