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首页> 外文期刊>Journal of pediatric hematology/oncology: Official journal of the American Society of Pediatric Hematology/Oncology >Scrub typhus-associated severe hemophagocytic lymphohistiocytosis with encephalomyelitis leading to permanent sequelae: A case report and review of the literature
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Scrub typhus-associated severe hemophagocytic lymphohistiocytosis with encephalomyelitis leading to permanent sequelae: A case report and review of the literature

机译：擦洗斑疹伤寒相关的严重噬血细胞性淋巴细胞增多与脑脊髓炎导致永久性后遗症：一例病例并文献复习

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摘要

Hemophagocytic lymphohistiocytosis (HLH) is a rare but potentially fatal disorder. There have been a few reports on HLH secondary to scrub typhus in adults. Here, we describe the case of a 9-year-old Korean girl who presented with the typical findings of HLH. Despite adequate antirickettsial and HLH treatment, the neurological impairment worsened and remained. This is the first case report of severe neurological impairment resulting from the very rare association of HLH with scrub typhus. Therefore, in endemic areas, a high index of suspicion for scrub typhus is warranted in patients presenting with HLH.
机译：吞噬性淋巴细胞组织细胞增生症（HLH）是一种罕见但可能致命的疾病。有关于成人继发性斑疹伤寒的HLH的一些报道。在这里，我们描述了一个9岁的韩国女孩的病例，该女孩表现出HLH的典型发现。尽管进行了充分的抗rick药治疗和HLH治疗，但神经功能缺损仍在恶化并保持。这是由于HLH与斑疹伤寒非常罕见的关联而导致的严重神经系统损害的第一例报告。因此，在流行地区，HLH患者应高度怀疑灌木斑疹伤寒。

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