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首页> 外文期刊>Clinics in dermatology >Surgical margins for resection of primary cutaneous melanoma.
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Surgical margins for resection of primary cutaneous melanoma.

机译:手术切缘切除原发性皮肤黑色素瘤。

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摘要

The increasing prevalence of melanoma in the United States is alarming. The limited efficacy of adjuvant therapies in successfully treating regional or distant disease underscores the importance of surgical treatment of primary cutaneous melanoma. The historic paradigm of wide margin excision (5 cm) with or with lymphadenectomy has been proven in multiple clinical trials to show no benefit of improved patient survival. Conservative margin resection of melanoma is a procedure of low morbidity that offers statistically identical outcomes and spares the patient excessive surgical efforts. Mohs micrographic surgery may have a role in the management of melanomas in anatomic sites where standard margins may prove difficult to achieve.
机译:在美国,黑色素瘤的患病率上升令人震惊。辅助疗法在成功治疗局部或远距离疾病中的功效有限,强调了外科治疗原发性皮肤黑色素瘤的重要性。淋巴结清扫术或联合淋巴结清扫术(5厘米)的宽边距切除术的历史性范例已在多项临床试验中得到证实,没有显示改善患者生存率的益处。黑色素瘤的保守性边缘切除术是一种低发病率的方法,可提供统计学上相同的结果,并为患者节省了过多的手术努力。莫氏显微外科手术可能在难以证明标准切缘的解剖部位黑色素瘤的治疗中发挥作用。

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