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首页> 外文期刊>Clinics in dermatology >Cutaneous signs of systemic disease.
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Cutaneous signs of systemic disease.

机译：全身性疾病的皮肤迹象。

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Commonly used dermatologic eponyms and characteristic skin signs are enormously helpful in guiding a diagnosis, even though they may not be pathonemonic. They include, on the nails, Aldrich-Mees' lines (syn.: Mees' lines), Beau's lines, Muehrcke's lines, Terry's nails, and half and half nails, often associated, respectively, with arsenic poisoning, acute stress or systemic illness, severe hypertension, liver disease and uremia, and, around the nails, Braverman's sign, associated with collagen-vascular disease. Elsewhere, one may see the Asboe-Hansen and Nikolsky's signs, indicative of the pemphigus group of diseases, Auspitz's sign, a classic finding in psoriasis, Borsieri's and Pasita's signs, seen in early scarlet fever, the butterfly rash, indicative of systemic lupus erythematosus, and the buffalo hump, seen in Cushing's disease and also in the more common corticosteroid toxicity. Gottron's papules and the heliotrope rash are signs of dermatomyositis. Janeway's lesions and Osler's nodes are seen in bacterial endocarditis. A Dennie-Morgan fold under the eye is seen in association with atopic disease. Koplik's spots are an early sign of rubeola. Fitzpatrick's sign is indicative of a benign lesion (dermatofibroma), whereas Hutchinson's sign is indicative of a malignant one (subungual melanoma). Petechiae are seen in many diseases, including fat embolization, particularly from a large bone fracture following trauma. Palpable purpura is indicative of leukocytoclastic vasculitis, and is an early, critical sign in Rickettsial diseases, including Rocky Mountain Spotted Fever, which must be diagnosed and treated early. Hyperpigmentation of areolae and scars is seen in Addison's disease. Acanthosis nigricans may indicate internal cancer, especially stomach cancer, whereas Bazex's syndrome occurs in synchrony with primary, usually squamous cancer, in the upper aerodigestive tract or metastatic cancer in cervical lymph nodes. Perioral pigmented macules or one or more cutaneous sebaceous neoplasms may be a sign of the Peutz-Jeghers or Muir-Torre syndrome, respectively, both associated also with intestinal polyps that have a malignant potential. Telangiectasiae in the perioral region may be associated with similar lesions internally in Osler-Weber-Rendu disease. Kerr's sign is indicative of spinal cord injury and Darier's sign of mastocytosis. Post proctoscopic periobital purpura (PPPP) is a phenomenon observed in some patients with systemic amyloidosis. Koebner's isomorphic response refers to the tendency of an established dermatosis, such as psoriasis, to arise in (a) site(s) of trauma, whereas Wolf's isotrophic response refers to a new dermatosis, such as tinea, not yet seen in the patient, arising in (a) site(s) of a former but different dermatosis, such as zoster.
机译：常用的皮肤科名称和特征性皮肤症状对指导诊断有很大帮助，即使它们可能不是病原体。它们包括在指甲上的Aldrich-Mees's线（同步：Mees's线），Beau's线，Muehrcke's线，Terry's指甲和一半和一半的指甲，分别与砷中毒，急性应激或全身性疾病相关，严重的高血压，肝病和尿毒症，以及指甲周围的Braverman征，与胶原蛋白血管疾病有关。在其他地方，可能会看到Asboe-Hansen和Nikolsky的体征，表明天疱疮是一组疾病，Auspitz的体征，是牛皮癣的典型发现，Borsieri和Pasita体征在早期猩红热中出现，出现了蝶形皮疹，表明系统性红斑狼疮，和水牛驼峰，见于库欣氏病以及更常见的皮质类固醇毒性。 Gottron的丘疹和天芥菜皮疹是皮肌炎的迹象。在细菌性心内膜炎中可见到珍妮威的病变和奥斯勒结。眼底出现丹妮-摩根褶皱与特应性疾病有关。 Koplik的景点是风疹的早期征兆。费兹帕特里克氏征表明存在良性病变（皮肤纤维瘤），而哈钦森氏征表明存在恶性病变（舌下黑色素瘤）。在许多疾病中都发现有tech虫病，包括脂肪栓塞，尤其是创伤后的大骨折。可触及的紫癜表示白细胞碎裂性血管炎，并且是立克次氏病（包括落基山斑热）的早期关键病征，必须尽早诊断和治疗。艾迪生氏病中可见乳晕和疤痕的色素沉着过度。黑棘皮病可能预示着内部癌症，尤其是胃癌，而巴兹克斯综合症与原发性，通常是鳞状上皮癌，上消化道消化道癌或宫颈淋巴结转移癌同步发生。周围色素斑或一种或多种皮肤皮脂腺肿瘤可能分别是Peutz-Jeghers或Muir-Torre综合征的征兆，两者均与具有恶性潜能的肠息肉有关。口腔周围的毛细血管扩张可能与Osler-Weber-Rendu病的内部相似病变有关。 Kerr征兆指示脊髓损伤，而Darier征兆表示肥大细胞增多症。内窥镜检查后的胆汁性紫癜（PPPP）是在一些系统性淀粉样变性患者中观察到的现象。 Koebner的同形反应是指在伤口的一个或多个部位出现确定的皮肤病（如牛皮癣）的趋势，而Wolf的同养性反应是指患者尚未见到的新的皮肤病（如癣），产生于先前但不同的皮肤病（如带状疱疹）的部位。

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