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首页> 外文期刊>Journal of Perinatal Medicine >Extracellular matrix components of the wall of umbilical cord vein and their alterations in pre-eclampsia.
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Extracellular matrix components of the wall of umbilical cord vein and their alterations in pre-eclampsia.

机译：子痫前期脐静脉壁的细胞外基质成分及其改变。

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摘要

Pre-eclampsia--edema, proteinuria, hypertension (EPH-gestosis) is one of the more common complications observed during pregnancy. The umbilical cord vein walls were taken from newborns delivered by healthy mothers (control material) and by mothers with polysymptomatic pre-eclampsia (investigated material). Normal saphenous vein walls were collected from adult subjects undergoing varicose vein surgery. The collagen content was measured by the assay of hydroxyproline. Elastin was determined according to Fastin Elastin Assay and gravimetrically. Glycosaminoglycans content was determined by uronic acids assay. The collagen content decreased in the pre-eclampsia material. The amount of soluble elastin increased in the investigated material. The insoluble elastin content decreased in the umbilical cord veins of newborns delivered by mothers with pre-eclampsia. Reconstructing the umbilical cord vein wall may disturb fetal blood flow and affect the vascular system in adulthood.
机译：子痫前期-水肿，蛋白尿，高血压（EPH-妊娠）是怀孕期间最常见的并发症之一。脐带静脉壁取自健康母亲（对照材料）和多症状先兆子痫的母亲（调查材料）。从接受静脉曲张手术的成年受试者中收集正常的隐静脉壁。通过羟脯氨酸的测定来测量胶原含量。弹性蛋白根据Fastin弹性蛋白测定法并通过重量分析法测定。糖胺聚糖含量通过糖醛酸测定法测定。子痫前期材料中的胶原含量降低。在研究的材料中可溶性弹性蛋白的量增加了。先兆子痫母亲分娩的新生儿的脐带静脉中的不溶弹性蛋白含量降低。重建脐带静脉壁可能会干扰胎儿的血流并影响成年期的血管系统。

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